Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis

FXR is a member of the nuclear receptor superfamily and bile acids are endogenous ligands of FXR. FXR activation has recently been reported to inhibit intestinal inflammation and tumour development. This study aimed to investigate whether the novel FXR agonist nelumal A, the active compound of the p...

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Detalles Bibliográficos
Autores principales: Miyazaki, Tsuneyuki, Shirakami, Yohei, Mizutani, Taku, Maruta, Akinori, Ideta, Takayasu, Kubota, Masaya, Sakai, Hiroyasu, Ibuka, Takashi, Genovese, Salvatore, Fiorito, Serena, Taddeo, Vito Alessandro, Epifano, Francesco, Tanaka, Takuji, Shimizu, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804240/
https://www.ncbi.nlm.nih.gov/pubmed/33436792
http://dx.doi.org/10.1038/s41598-020-79916-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804240/
https://www.ncbi.nlm.nih.gov/pubmed/33436792
http://dx.doi.org/10.1038/s41598-020-79916-5

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