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Structure and compositional analysis of aluminum oxyhydroxide adsorbed pertussis vaccine
PURPOSE: The goal of this study was to characterize an acellular pertussis vaccine (Tdap) containing genetically modified pertussis toxin (gdPT) and TLR agonist adsorbed to AlOOH adjuvant. METHODS: Several analytical tools including nanoDSF, FTIR, and LD were used to examine the conformation of nove...
Autores principales: | Duprez, Jessica, Kalbfleisch, Kristen, Deshmukh, Sasmit, Payne, Jessie, Haer, Manjit, Williams, Wayne, Durowoju, Ibrahim, Kirkitadze, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804342/ https://www.ncbi.nlm.nih.gov/pubmed/33489011 http://dx.doi.org/10.1016/j.csbj.2020.12.023 |
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