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Integrative microRNA and gene expression analysis identifies new epigenetically regulated microRNAs mediating taxane resistance in ovarian cancer

Taxane is a family of front-line chemotherapeutic agents against ovarian cancer (OC). The therapeutic efficacy is frequently counteracted by the development of chemoresistance, leading to high rates of relapse in OC patients. The role(s) of microRNAs (miRNAs) in cancer chemoresistance had been suppo...

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Detalles Bibliográficos
Autores principales: Hassan, Mohamed K., Waly, Amr A., Elsayed, Waheba, Keshk, Sarah, Allam, Walaa Ramadan, El-khamisy, Sherif F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804410/
https://www.ncbi.nlm.nih.gov/pubmed/33436648
http://dx.doi.org/10.1038/s41598-020-78596-5