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LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH

It remains unclear how hepatic steatosis links to inflammation. Leukocyte cell-derived chemotaxin 2 (LECT2) is a hepatokine that senses fat in the liver and is upregulated prior to weight gain. The aim of this study was to investigate the significance of LECT2 in the development of nonalcoholic stea...

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Detalles Bibliográficos
Autores principales:	Takata, Noboru, Ishii, Kiyo-aki, Takayama, Hiroaki, Nagashimada, Mayumi, Kamoshita, Kyoko, Tanaka, Takeo, Kikuchi, Akihiro, Takeshita, Yumie, Matsumoto, Yukako, Ota, Tsuguhito, Yamamoto, Yasuhiko, Yamagoe, Satoshi, Seki, Akihiro, Sakai, Yoshio, Kaneko, Shuichi, Takamura, Toshinari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804418/ https://www.ncbi.nlm.nih.gov/pubmed/33436955 http://dx.doi.org/10.1038/s41598-020-80689-0

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