Cargando…
Generation of proliferating human adult hepatocytes using optimized 3D culture conditions
Generating the proliferation of differentiated normal adult human hepatocytes is a major challenge and an expected central step in understanding the microenvironmental conditions that regulate the phenotype of human hepatocytes in vitro. In this work, we described optimized 3D culture conditions of...
Autores principales: | Rose, Sophie, Ezan, Frédéric, Cuvellier, Marie, Bruyère, Arnaud, Legagneux, Vincent, Langouët, Sophie, Baffet, Georges |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804446/ https://www.ncbi.nlm.nih.gov/pubmed/33436872 http://dx.doi.org/10.1038/s41598-020-80019-4 |
Ejemplares similares
-
Integrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERK-dependent pathways in transformed cells
por: Nizard, Philippe, et al.
Publicado: (2014) -
A modeling approach to evaluate the balance between bioactivation and detoxification of MeIQx in human hepatocytes
por: Delannée, Victorien, et al.
Publicado: (2017) -
Determination of extracellular matrix collagen fibril architectures and pathological remodeling by polarization dependent second harmonic microscopy
por: Rouède, Denis, et al.
Publicado: (2017) -
The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control
por: Guégan, Jean-Philippe, et al.
Publicado: (2012) -
ACTIVE PROLIFERATION OF MOUSE HEPATOCYTES IN PRIMARY CULTURE UNDER DEFINED CONDITIONS AS COMPARED TO RAT HEPATOCYTES
por: Sawada, Norimasa, et al.
Publicado: (1988)