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CCAAT/Enhancer-binding protein delta mediates glioma stem-like cell enrichment and ATP-binding cassette transporter ABCA1 activation for temozolomide resistance in glioblastoma

Glioblastoma (GBM) is the most aggressive brain tumor and relapses after chemo- or radiotherapy in a short time. The anticancer drug temozolamide (TMZ) is commonly used for GBM treatment, but glioma stem-like cells (GSCs) often lead to drug resistance and therapeutic failure. To date, the mechanism...

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Detalles Bibliográficos
Autores principales: Wang, Shao-Ming, Lin, Wen-Chi, Lin, Hong-Yi, Chen, Yen-Lin, Ko, Chiung-Yuan, Wang, Ju-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7804954/
https://www.ncbi.nlm.nih.gov/pubmed/33436575
http://dx.doi.org/10.1038/s41420-020-00399-4

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