Cargando…

Chinese herbal extract granules combined with 5-aminosalicylic acid for patients with moderately active ulcerative colitis: study protocol for a multicenter randomized double-blind placebo-controlled trial

BACKGROUND: Ulcerative colitis (UC) is an intestinal inflammatory disease characterized by inflammation of the colonic mucosa. With unknown pathogenesis, it has become a chronic lifetime disorder worldwide. In patients with moderately active UC, several therapies (e.g., aminosalicylates, corticoster...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Zhaofeng, Zheng, Kai, Zou, Jiandong, Gu, Peiqing, Xing, Jing, Zhang, Lu, Zhu, Lei, Shen, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805063/ https://www.ncbi.nlm.nih.gov/pubmed/33441157 http://dx.doi.org/10.1186/s13063-020-05012-8

Ejemplares similares

Patient Preference and Adherence to Aminosalicylates for the Treatment of Ulcerative Colitis
por: Tripathi, Kartikeya, et al.
Publicado: (2021)

5-Aminosalicylic acid aggravates colitis mimicking exacerbation of ulcerative colitis
por: Miyoshi, Jun, et al.
Publicado: (2018)

Medical Management of Ulcerative Colitis with a Specific Focus on 5-Aminosalicylates
por: Freeman, Hugh James
Publicado: (2012)

The Synergistic Effects of 5-Aminosalicylic Acid and Vorinostat in the Treatment of Ulcerative Colitis
por: He, Long, et al.
Publicado: (2021)

Significance of 5-Aminosalicylic Acid Intolerance in the Clinical Management of Ulcerative Colitis
por: Mikami, Yohei, et al.
Publicado: (2023)

Efficacy of Chuanxiong Ding Tong Herbal Formula Granule in the Treatment and Prophylactic of Migraine Patients: A Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial
por: Fu, Caihong, et al.
Publicado: (2012)

5-Aminosalicylic Acid Alters the Gut Bacterial Microbiota in Patients With Ulcerative Colitis
por: Xu, Jun, et al.
Publicado: (2018)

Synthesis and evaluation of a prodrug of 5-aminosalicylic acid for the treatment of ulcerative colitis
por: Yan, Yan, et al.
Publicado: (2019)

Factors associated with low adherence to oral 5-aminosalicylic acid in patients with ulcerative colitis
por: Lee, Jin, et al.
Publicado: (2019)

Colon-targeting mutual prodrugs of 5-aminosalicylic acid and butyrate for the treatment of ulcerative colitis
por: Yan, Yan, et al.
Publicado: (2018)

Additive effect of probiotics (Mutaflor) on 5-aminosalicylic acid therapy in patients with ulcerative colitis
por: Park, Soo-Kyung, et al.
Publicado: (2022)

Fecal microbiota transplantation treatment for refractory ulcerative colitis with allergy to 5-aminosalicylic acid: A case report
por: Wang, Hong-Gang, et al.
Publicado: (2018)

Combination of corticosteroids and 5-aminosalicylates or corticosteroids alone for patients with moderate-severe active ulcerative colitis: A global survey of physicians' practice
por: Ben-Horin, Shomron, et al.
Publicado: (2017)

Efficacy and safety of herbal medicine (Binafuxi granules) for the common cold with fever: A multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial
por: Liu, Xuemei, et al.
Publicado: (2023)

Efficacy and safety of oral beclomethasone dipropionate and budesonide MMX versus 5-aminosalicylates or placebo in ulcerative colitis: a systematic review and meta-analysis
por: Barberio, Brigida, et al.
Publicado: (2023)

5-Aminosalicylates Reduce the Risk of Colorectal Neoplasia in Patients with Ulcerative Colitis: An Updated Meta-Analysis
por: Zhao, Li-Na, et al.
Publicado: (2014)

A New Chinese Medicine Intestine Formula Greatly Improves the Effect of Aminosalicylate on Ulcerative Colitis
por: Liu, Baohai, et al.
Publicado: (2017)

Clinical Background Factors as Predictors of the Efficacy of 5-Aminosalicylic Acid Suppositories in Patients with Ulcerative Colitis
por: Uchiyama, Kazuhiko, et al.
Publicado: (2023)

Mesalazine granules promote disease clearance in patients with mild‐to‐moderate ulcerative colitis
por: Kruis, Wolfgang, et al.
Publicado: (2023)

Efficacy and Safety of Chinese Herbal Formula Granules in Treating Chronic Kidney Disease Stage 3: A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial
por: Zhao, Jing, et al.
Publicado: (2020)

Ulcerative Colitis Impairs the Acylethanolamide-Based Anti-Inflammatory System Reversal by 5-Aminosalicylic Acid and Glucocorticoids
por: Suárez, Juan, et al.
Publicado: (2012)

Combination of Azathioprine and Aminosalicylate Treatment Prevent Risk of Cardiovascular Disease in Women with Ulcerative Colitis by Reducing Inflammation
por: dos Santos, Lana Claudinez, et al.
Publicado: (2015)

Comparison of maintenance effect of probiotics and aminosalicylates on ulcerative colitis: A meta-analysis of randomized controlled trials
por: Jiang, Yong, et al.
Publicado: (2016)

Mucosal 5‐aminosalicylic acid concentration, drug formulation and mucosal microbiome in patients with quiescent ulcerative colitis
por: Olaisen, Maya, et al.
Publicado: (2019)

Therapeutic Efficacy of the Combination Therapy of Corticosteroids and 5-Aminosalicylic Acid for Treatment of Pyoderma Gangrenosum with Ulcerative Colitis
por: Chen, Wei, et al.
Publicado: (2020)

Comparison of effects of aminosalicylic acid, glucocorticoids and immunosuppressive agents on the expression of multidrug-resistant genes in ulcerative colitis
por: Chen, Yan, et al.
Publicado: (2022)

Traditional Chinese medicine for mild-to-moderate ulcerative colitis: Protocol for a network meta-analysis of randomized controlled trials
por: Shen, Zhaofeng, et al.
Publicado: (2019)

Efficacy and Safety of Ganduqing Granules in Treating the Common Cold: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
por: Wang, Yilan, et al.
Publicado: (2022)

The effects of qishen granules for patients with chronic heart failure: A multicenter randomized double-blind placebo-controlled trial
por: Du, Kangjia, et al.
Publicado: (2022)

Probiotics combined with aminosalicylic acid affiliates remission of ulcerative colitis: a meta-analysis of randomized controlled trial
por: Peng, Lijun, et al.
Publicado: (2019)

5-Aminosalicylic acid intolerance is associated with a risk of adverse clinical outcomes and dysbiosis in patients with ulcerative colitis
por: Mizuno, Shinta, et al.
Publicado: (2020)

Mucosal concentrations of N‐acetyl‐5‐aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine
por: Fukuda, Tomohiro, et al.
Publicado: (2020)

Vedolizumab in Japanese patients with ulcerative colitis: A Phase 3, randomized, double-blind, placebo-controlled study
por: Motoya, Satoshi, et al.
Publicado: (2019)

Low dose oral curcumin is not effective in induction of remission in mild to moderate ulcerative colitis: Results from a randomized double blind placebo controlled trial
por: Kedia, Saurabh, et al.
Publicado: (2017)

Herbal Medicine in the Treatment of Ulcerative Colitis
por: Ke, Fei, et al.
Publicado: (2012)

Effect of acid-reducing agents on clinical relapse in ulcerative colitis with pH-dependent-released 5-aminosalicylic acid: a multicenter retrospective study in Japan
por: Shimodaira, Yosuke, et al.
Publicado: (2021)

Efficacy and Safety of Wenbu Zhibi Granule in Patients with Ankylosing Spondylitis: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial
por: Zhang, Helou, et al.
Publicado: (2021)

Efficacy and safety of Kangfuxin liquid combined with aminosalicylic acid for the treatment of ulcerative colitis: A systematic review and meta-analysis
por: Li, Hui-biao, et al.
Publicado: (2018)

Predictive factors of relapse after dose reduction of oral 5-aminosalicylic acid in patients with ulcerative colitis in the remission phase
por: Madarame, Akira, et al.
Publicado: (2021)

Factors associated with the persistence of oral 5-aminosalicylic acid monotherapy in ulcerative colitis: a nationwide Norwegian cohort study
por: Fossmark, Reidar, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jerbk6ts3rkh0hei7fic8nej7c