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Circular RNA circ_0081001 knockdown enhances methotrexate sensitivity in osteosarcoma cells by regulating miR-494-3p/TGM2 axis

BACKGROUND: Circular RNAs (circRNAs) have been shown to participate in the chemoresistance and tumorigenesis of multiple cancers. The purpose of this research was to investigate the function of circ_0081001 in methotrexate (MTX) resistance of osteosarcoma (OS) and its potential molecular mechanism....

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Detalles Bibliográficos
Autores principales: Wei, Wei, Ji, Liefeng, Duan, Wanli, Zhu, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805151/
https://www.ncbi.nlm.nih.gov/pubmed/33435987
http://dx.doi.org/10.1186/s13018-020-02169-5

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