Overcoming bioprocess bottlenecks in the large-scale expansion of high-quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors

BACKGROUND: Human induced pluripotent stem cells (hiPSCs) hold enormous promise in accelerating breakthroughs in understanding human development, drug screening, disease modeling, and cell and gene therapies. Their potential, however, has been bottlenecked in a mostly laboratory setting due to biopr...

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Detalles Bibliográficos
Autores principales: Borys, Breanna S., Dang, Tiffany, So, Tania, Rohani, Leili, Revay, Tamas, Walsh, Tylor, Thompson, Madalynn, Argiropoulos, Bob, Rancourt, Derrick E., Jung, Sunghoon, Hashimura, Yas, Lee, Brian, Kallos, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805206/
https://www.ncbi.nlm.nih.gov/pubmed/33436078
http://dx.doi.org/10.1186/s13287-020-02109-4

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