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Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

BACKGROUND: The SARS-CoV-2 pandemic is currently leading to increasing numbers of COVID-19 patients all over the world. Clinical presentations range from asymptomatic, mild respiratory tract infection, to severe cases with acute respiratory distress syndrome, respiratory failure, and death. Reports...

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Detalles Bibliográficos
Autores principales: Aschenbrenner, Anna C., Mouktaroudi, Maria, Krämer, Benjamin, Oestreich, Marie, Antonakos, Nikolaos, Nuesch-Germano, Melanie, Gkizeli, Konstantina, Bonaguro, Lorenzo, Reusch, Nico, Baßler, Kevin, Saridaki, Maria, Knoll, Rainer, Pecht, Tal, Kapellos, Theodore S., Doulou, Sarandia, Kröger, Charlotte, Herbert, Miriam, Holsten, Lisa, Horne, Arik, Gemünd, Ioanna D., Rovina, Nikoletta, Agrawal, Shobhit, Dahm, Kilian, van Uelft, Martina, Drews, Anna, Lenkeit, Lena, Bruse, Niklas, Gerretsen, Jelle, Gierlich, Jannik, Becker, Matthias, Händler, Kristian, Kraut, Michael, Theis, Heidi, Mengiste, Simachew, De Domenico, Elena, Schulte-Schrepping, Jonas, Seep, Lea, Raabe, Jan, Hoffmeister, Christoph, ToVinh, Michael, Keitel, Verena, Rieke, Gereon, Talevi, Valentina, Skowasch, Dirk, Aziz, N. Ahmad, Pickkers, Peter, van de Veerdonk, Frank L., Netea, Mihai G., Schultze, Joachim L., Kox, Matthijs, Breteler, Monique M. B., Nattermann, Jacob, Koutsoukou, Antonia, Giamarellos-Bourboulis, Evangelos J., Ulas, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805430/
https://www.ncbi.nlm.nih.gov/pubmed/33441124
http://dx.doi.org/10.1186/s13073-020-00823-5