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MVA Vector Vaccines Inhibit SARS CoV-2 Replication in Upper and Lower Respiratory Tracts of Transgenic Mice and Prevent Lethal Disease

Replication-restricted modified vaccinia virus Ankara (MVA) is a licensed smallpox vaccine and numerous clinical studies investigating recombinant MVAs (rMVAs) as vectors for prevention of other infectious diseases have been completed or are in progress. Two rMVA COVID-19 vaccine trials are at an in...

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Detalles Bibliográficos
Autores principales: Liu, Ruikang, Americo, Jeffrey L., Cotter, Catherine A., Earl, Patricia L., Erez, Noam, Peng, Chen, Moss, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805450/
https://www.ncbi.nlm.nih.gov/pubmed/33442693
http://dx.doi.org/10.1101/2020.12.30.424878