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Bilateral Hydronephrosis Secondary to Giant Cell Tumor of the Sacrum

Sacral giant cell tumors (GCTs) are rare entities that exhibit slow progressive growth and become clinically apparent when they reach a considerable size. The current case report discusses the presentation, investigation, and management of a young male patient diagnosed with a large sacral mass. A 1...

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Autores principales: Rehman, Omer Farooq, Hussain, Amer K, Ummair, Mohammad, Umair, Musab, Waqar, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805515/
https://www.ncbi.nlm.nih.gov/pubmed/33489516
http://dx.doi.org/10.7759/cureus.12099
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author Rehman, Omer Farooq
Hussain, Amer K
Ummair, Mohammad
Umair, Musab
Waqar, Muhammad
author_facet Rehman, Omer Farooq
Hussain, Amer K
Ummair, Mohammad
Umair, Musab
Waqar, Muhammad
author_sort Rehman, Omer Farooq
collection PubMed
description Sacral giant cell tumors (GCTs) are rare entities that exhibit slow progressive growth and become clinically apparent when they reach a considerable size. The current case report discusses the presentation, investigation, and management of a young male patient diagnosed with a large sacral mass. A 17-year-old male patient presented with uremia, bilateral lumbar pain, and severe weakness of his lower extremities. Imaging revealed a midline sacral mass causing bilateral upper tract obstruction. The patient underwent bilateral nephrostomies followed by a partial en bloc sacrectomy and curettage of the tumor bulk. Histopathology revealed a giant cell tumor of the sacrum. Postoperatively, the patient received adjuvant radiotherapy and rehabilitation for his neurological symptoms. Sacral GCTs are essentially benign but behave like a malignant tumor in view of frequent recurrences and reports of malignant transformation. Surgery with wide local excision remains the ideal modality for complete clearance of sacral tumors. Nevertheless, limitations include their large size, difficult operative access, risk of fatal intraoperative bleeding, and inevitable high postoperative morbidity.
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spelling pubmed-78055152021-01-21 Bilateral Hydronephrosis Secondary to Giant Cell Tumor of the Sacrum Rehman, Omer Farooq Hussain, Amer K Ummair, Mohammad Umair, Musab Waqar, Muhammad Cureus Urology Sacral giant cell tumors (GCTs) are rare entities that exhibit slow progressive growth and become clinically apparent when they reach a considerable size. The current case report discusses the presentation, investigation, and management of a young male patient diagnosed with a large sacral mass. A 17-year-old male patient presented with uremia, bilateral lumbar pain, and severe weakness of his lower extremities. Imaging revealed a midline sacral mass causing bilateral upper tract obstruction. The patient underwent bilateral nephrostomies followed by a partial en bloc sacrectomy and curettage of the tumor bulk. Histopathology revealed a giant cell tumor of the sacrum. Postoperatively, the patient received adjuvant radiotherapy and rehabilitation for his neurological symptoms. Sacral GCTs are essentially benign but behave like a malignant tumor in view of frequent recurrences and reports of malignant transformation. Surgery with wide local excision remains the ideal modality for complete clearance of sacral tumors. Nevertheless, limitations include their large size, difficult operative access, risk of fatal intraoperative bleeding, and inevitable high postoperative morbidity. Cureus 2020-12-15 /pmc/articles/PMC7805515/ /pubmed/33489516 http://dx.doi.org/10.7759/cureus.12099 Text en Copyright © 2020, Rehman et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Urology
Rehman, Omer Farooq
Hussain, Amer K
Ummair, Mohammad
Umair, Musab
Waqar, Muhammad
Bilateral Hydronephrosis Secondary to Giant Cell Tumor of the Sacrum
title Bilateral Hydronephrosis Secondary to Giant Cell Tumor of the Sacrum
title_full Bilateral Hydronephrosis Secondary to Giant Cell Tumor of the Sacrum
title_fullStr Bilateral Hydronephrosis Secondary to Giant Cell Tumor of the Sacrum
title_full_unstemmed Bilateral Hydronephrosis Secondary to Giant Cell Tumor of the Sacrum
title_short Bilateral Hydronephrosis Secondary to Giant Cell Tumor of the Sacrum
title_sort bilateral hydronephrosis secondary to giant cell tumor of the sacrum
topic Urology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805515/
https://www.ncbi.nlm.nih.gov/pubmed/33489516
http://dx.doi.org/10.7759/cureus.12099
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