A Rare Presentation of Parvovirus Induced Pure Red Cell Aplasia in Elderly Male With Inclusion Body Myositis

Pure red cell aplasia (PRCA) is a rare condition leading to erythroid bone marrow failure. Parvovirus is one of the rare causes of PRCA in older adults. We present a 73-year-old man on high dose prednisone who presented with rapid functional decline and shortness of breath and was found to have norm...

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Autores principales: Mandal, Shobha, Shah, Ravindra, Lowry, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805531/
https://www.ncbi.nlm.nih.gov/pubmed/33489512
http://dx.doi.org/10.7759/cureus.12095
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author Mandal, Shobha
Shah, Ravindra
Lowry, Philip
author_facet Mandal, Shobha
Shah, Ravindra
Lowry, Philip
author_sort Mandal, Shobha
collection PubMed
description Pure red cell aplasia (PRCA) is a rare condition leading to erythroid bone marrow failure. Parvovirus is one of the rare causes of PRCA in older adults. We present a 73-year-old man on high dose prednisone who presented with rapid functional decline and shortness of breath and was found to have normocytic normochromic anemia with low reticulocyte counts. On further workup, he was found to have elevated immunoglobulin M (IgM) titer of parvovirus B-19 antibody. The patient was managed with supportive care with blood transfusion, hydration and had improvement in his symptoms.
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spelling pubmed-78055312021-01-21 A Rare Presentation of Parvovirus Induced Pure Red Cell Aplasia in Elderly Male With Inclusion Body Myositis Mandal, Shobha Shah, Ravindra Lowry, Philip Cureus Infectious Disease Pure red cell aplasia (PRCA) is a rare condition leading to erythroid bone marrow failure. Parvovirus is one of the rare causes of PRCA in older adults. We present a 73-year-old man on high dose prednisone who presented with rapid functional decline and shortness of breath and was found to have normocytic normochromic anemia with low reticulocyte counts. On further workup, he was found to have elevated immunoglobulin M (IgM) titer of parvovirus B-19 antibody. The patient was managed with supportive care with blood transfusion, hydration and had improvement in his symptoms. Cureus 2020-12-15 /pmc/articles/PMC7805531/ /pubmed/33489512 http://dx.doi.org/10.7759/cureus.12095 Text en Copyright © 2020, Mandal et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Infectious Disease
Mandal, Shobha
Shah, Ravindra
Lowry, Philip
A Rare Presentation of Parvovirus Induced Pure Red Cell Aplasia in Elderly Male With Inclusion Body Myositis
title A Rare Presentation of Parvovirus Induced Pure Red Cell Aplasia in Elderly Male With Inclusion Body Myositis
title_full A Rare Presentation of Parvovirus Induced Pure Red Cell Aplasia in Elderly Male With Inclusion Body Myositis
title_fullStr A Rare Presentation of Parvovirus Induced Pure Red Cell Aplasia in Elderly Male With Inclusion Body Myositis
title_full_unstemmed A Rare Presentation of Parvovirus Induced Pure Red Cell Aplasia in Elderly Male With Inclusion Body Myositis
title_short A Rare Presentation of Parvovirus Induced Pure Red Cell Aplasia in Elderly Male With Inclusion Body Myositis
title_sort rare presentation of parvovirus induced pure red cell aplasia in elderly male with inclusion body myositis
topic Infectious Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805531/
https://www.ncbi.nlm.nih.gov/pubmed/33489512
http://dx.doi.org/10.7759/cureus.12095
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