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Pathophysiological subtypes of Alzheimer’s disease based on cerebrospinal fluid proteomics
Alzheimer’s disease is biologically heterogeneous, and detailed understanding of the processes involved in patients is critical for development of treatments. CSF contains hundreds of proteins, with concentrations reflecting ongoing (patho)physiological processes. This provides the opportunity to st...
Autores principales: | Tijms, Betty M, Gobom, Johan, Reus, Lianne, Jansen, Iris, Hong, Shengjun, Dobricic, Valerija, Kilpert, Fabian, ten Kate, Mara, Barkhof, Frederik, Tsolaki, Magda, Verhey, Frans R J, Popp, Julius, Martinez-Lage, Pablo, Vandenberghe, Rik, Lleó, Alberto, Molinuevo, José Luís, Engelborghs, Sebastiaan, Bertram, Lars, Lovestone, Simon, Streffer, Johannes, Vos, Stephanie, Bos, Isabelle, Blennow, Kaj, Scheltens, Philip, Teunissen, Charlotte E, Zetterberg, Henrik, Visser, Pieter Jelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805814/ https://www.ncbi.nlm.nih.gov/pubmed/33439986 http://dx.doi.org/10.1093/brain/awaa325 |
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