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A Perspective on Innovating the Chemistry Lab Bench

Innovating on the design and function of the chemical bench remains a quintessential challenge of the ages. It requires a deep understanding of the important role chemistry plays in scientific discovery as well a first principles approach to addressing the gaps in how work gets done at the bench. Th...

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Autores principales: Godfrey, Alexander G., Michael, Samuel G., Sittampalam, Gurusingham Sitta, Zahoránszky-Köhalmi, Gergely
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805875/
https://www.ncbi.nlm.nih.gov/pubmed/33501193
http://dx.doi.org/10.3389/frobt.2020.00024
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author Godfrey, Alexander G.
Michael, Samuel G.
Sittampalam, Gurusingham Sitta
Zahoránszky-Köhalmi, Gergely
author_facet Godfrey, Alexander G.
Michael, Samuel G.
Sittampalam, Gurusingham Sitta
Zahoránszky-Köhalmi, Gergely
author_sort Godfrey, Alexander G.
collection PubMed
description Innovating on the design and function of the chemical bench remains a quintessential challenge of the ages. It requires a deep understanding of the important role chemistry plays in scientific discovery as well a first principles approach to addressing the gaps in how work gets done at the bench. This perspective examines how one might explore designing and creating a sustainable new standard for advancing automated chemistry bench itself. We propose how this might be done by leveraging recent advances in laboratory automation whereby integrating the latest synthetic, analytical and information technologies, and AI/ML algorithms within a standardized framework, maximizes the value of the data generated and the broader utility of such systems. Although the context of this perspective focuses on the design of advancing molecule of potential therapeutic value, it would not be a stretch to contemplate how such systems could be applied to other applied disciplines like advanced materials, foodstuffs, or agricultural product development.
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spelling pubmed-78058752021-01-25 A Perspective on Innovating the Chemistry Lab Bench Godfrey, Alexander G. Michael, Samuel G. Sittampalam, Gurusingham Sitta Zahoránszky-Köhalmi, Gergely Front Robot AI Robotics and AI Innovating on the design and function of the chemical bench remains a quintessential challenge of the ages. It requires a deep understanding of the important role chemistry plays in scientific discovery as well a first principles approach to addressing the gaps in how work gets done at the bench. This perspective examines how one might explore designing and creating a sustainable new standard for advancing automated chemistry bench itself. We propose how this might be done by leveraging recent advances in laboratory automation whereby integrating the latest synthetic, analytical and information technologies, and AI/ML algorithms within a standardized framework, maximizes the value of the data generated and the broader utility of such systems. Although the context of this perspective focuses on the design of advancing molecule of potential therapeutic value, it would not be a stretch to contemplate how such systems could be applied to other applied disciplines like advanced materials, foodstuffs, or agricultural product development. Frontiers Media S.A. 2020-02-25 /pmc/articles/PMC7805875/ /pubmed/33501193 http://dx.doi.org/10.3389/frobt.2020.00024 Text en Copyright © 2020 Godfrey, Michael, Sittampalam and Zahoránszky-Köhalmi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Robotics and AI
Godfrey, Alexander G.
Michael, Samuel G.
Sittampalam, Gurusingham Sitta
Zahoránszky-Köhalmi, Gergely
A Perspective on Innovating the Chemistry Lab Bench
title A Perspective on Innovating the Chemistry Lab Bench
title_full A Perspective on Innovating the Chemistry Lab Bench
title_fullStr A Perspective on Innovating the Chemistry Lab Bench
title_full_unstemmed A Perspective on Innovating the Chemistry Lab Bench
title_short A Perspective on Innovating the Chemistry Lab Bench
title_sort perspective on innovating the chemistry lab bench
topic Robotics and AI
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805875/
https://www.ncbi.nlm.nih.gov/pubmed/33501193
http://dx.doi.org/10.3389/frobt.2020.00024
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