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A Perspective on Innovating the Chemistry Lab Bench
Innovating on the design and function of the chemical bench remains a quintessential challenge of the ages. It requires a deep understanding of the important role chemistry plays in scientific discovery as well a first principles approach to addressing the gaps in how work gets done at the bench. Th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805875/ https://www.ncbi.nlm.nih.gov/pubmed/33501193 http://dx.doi.org/10.3389/frobt.2020.00024 |
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author | Godfrey, Alexander G. Michael, Samuel G. Sittampalam, Gurusingham Sitta Zahoránszky-Köhalmi, Gergely |
author_facet | Godfrey, Alexander G. Michael, Samuel G. Sittampalam, Gurusingham Sitta Zahoránszky-Köhalmi, Gergely |
author_sort | Godfrey, Alexander G. |
collection | PubMed |
description | Innovating on the design and function of the chemical bench remains a quintessential challenge of the ages. It requires a deep understanding of the important role chemistry plays in scientific discovery as well a first principles approach to addressing the gaps in how work gets done at the bench. This perspective examines how one might explore designing and creating a sustainable new standard for advancing automated chemistry bench itself. We propose how this might be done by leveraging recent advances in laboratory automation whereby integrating the latest synthetic, analytical and information technologies, and AI/ML algorithms within a standardized framework, maximizes the value of the data generated and the broader utility of such systems. Although the context of this perspective focuses on the design of advancing molecule of potential therapeutic value, it would not be a stretch to contemplate how such systems could be applied to other applied disciplines like advanced materials, foodstuffs, or agricultural product development. |
format | Online Article Text |
id | pubmed-7805875 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78058752021-01-25 A Perspective on Innovating the Chemistry Lab Bench Godfrey, Alexander G. Michael, Samuel G. Sittampalam, Gurusingham Sitta Zahoránszky-Köhalmi, Gergely Front Robot AI Robotics and AI Innovating on the design and function of the chemical bench remains a quintessential challenge of the ages. It requires a deep understanding of the important role chemistry plays in scientific discovery as well a first principles approach to addressing the gaps in how work gets done at the bench. This perspective examines how one might explore designing and creating a sustainable new standard for advancing automated chemistry bench itself. We propose how this might be done by leveraging recent advances in laboratory automation whereby integrating the latest synthetic, analytical and information technologies, and AI/ML algorithms within a standardized framework, maximizes the value of the data generated and the broader utility of such systems. Although the context of this perspective focuses on the design of advancing molecule of potential therapeutic value, it would not be a stretch to contemplate how such systems could be applied to other applied disciplines like advanced materials, foodstuffs, or agricultural product development. Frontiers Media S.A. 2020-02-25 /pmc/articles/PMC7805875/ /pubmed/33501193 http://dx.doi.org/10.3389/frobt.2020.00024 Text en Copyright © 2020 Godfrey, Michael, Sittampalam and Zahoránszky-Köhalmi. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Robotics and AI Godfrey, Alexander G. Michael, Samuel G. Sittampalam, Gurusingham Sitta Zahoránszky-Köhalmi, Gergely A Perspective on Innovating the Chemistry Lab Bench |
title | A Perspective on Innovating the Chemistry Lab Bench |
title_full | A Perspective on Innovating the Chemistry Lab Bench |
title_fullStr | A Perspective on Innovating the Chemistry Lab Bench |
title_full_unstemmed | A Perspective on Innovating the Chemistry Lab Bench |
title_short | A Perspective on Innovating the Chemistry Lab Bench |
title_sort | perspective on innovating the chemistry lab bench |
topic | Robotics and AI |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7805875/ https://www.ncbi.nlm.nih.gov/pubmed/33501193 http://dx.doi.org/10.3389/frobt.2020.00024 |
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