Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine

Terminally differentiated murine osteocytes and adipocytes can be reprogrammed using platelet-derived growth factor–AB and 5-azacytidine into multipotent stem cells with stromal cell characteristics. We have now optimized culture conditions to reprogram human adipocytes into induced multipotent stem...

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Detalles Bibliográficos
Autores principales: Yeola, Avani, Subramanian, Shruthi, Oliver, Rema A., Lucas, Christine A., Thoms, Julie A. I., Yan, Feng, Olivier, Jake, Chacon, Diego, Tursky, Melinda L., Srivastava, Pallavi, Potas, Jason R., Hung, Tzongtyng, Power, Carl, Hardy, Philip, Ma, David D., Kilian, Kristopher A., McCarroll, Joshua, Kavallaris, Maria, Hesson, Luke B., Beck, Dominik, Curtis, David J., Wong, Jason W. H., Hardeman, Edna C., Walsh, William R., Mobbs, Ralph, Chandrakanthan, Vashe, Pimanda, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806226/
https://www.ncbi.nlm.nih.gov/pubmed/33523875
http://dx.doi.org/10.1126/sciadv.abd1929

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