Cargando…
The Arp1/11 minifilament of dynactin primes the endosomal Arp2/3 complex
Dendritic actin networks develop from a first actin filament through branching by the Arp2/3 complex. At the surface of endosomes, the WASH complex activates the Arp2/3 complex and interacts with the capping protein for unclear reasons. Here, we show that the WASH complex interacts with dynactin and...
Autores principales: | Fokin, Artem I., David, Violaine, Oguievetskaia, Ksenia, Derivery, Emmanuel, Stone, Caroline E., Cao, Luyan, Rocques, Nathalie, Molinie, Nicolas, Henriot, Véronique, Aumont-Nicaise, Magali, Hinckelmann, Maria-Victoria, Saudou, Frédéric, Le Clainche, Christophe, Carter, Andrew P., Romet-Lemonne, Guillaume, Gautreau, Alexis M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806238/ https://www.ncbi.nlm.nih.gov/pubmed/33523880 http://dx.doi.org/10.1126/sciadv.abd5956 |
Ejemplares similares
-
Analysis of Dynactin Subcomplexes Reveals a Novel Actin-Related Protein Associated with the Arp1 Minifilament Pointed End
por: Eckley, D. Mark, et al.
Publicado: (1999) -
Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex
por: Simanov, Gleb, et al.
Publicado: (2021) -
Regulation of branched versus linear Arp2/3‐generated actin filaments
por: Cao, Luyan, et al.
Publicado: (2023) -
Dynactin integrity depends upon direct binding of dynamitin to Arp1
por: Cheong, Frances Ka Yan, et al.
Publicado: (2014) -
Actin Polymerization Controls the Organization of WASH Domains at the Surface of Endosomes
por: Derivery, Emmanuel, et al.
Publicado: (2012)