Checkpoint inhibition of origin firing prevents inappropriate replication outside of S-phase

Checkpoints maintain the order of cell cycle events during DNA damage or incomplete replication. How the checkpoint response is tailored to different phases of the cell cycle remains poorly understood. The S-phase checkpoint for example results in the slowing of replication, which in budding yeast o...

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Detalles Bibliográficos
Autores principales: Johnson, Mark C, Can, Geylani, Santos, Miguel Monteiro, Alexander, Diana, Zegerman, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806266/
https://www.ncbi.nlm.nih.gov/pubmed/33399537
http://dx.doi.org/10.7554/eLife.63589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806266/
https://www.ncbi.nlm.nih.gov/pubmed/33399537
http://dx.doi.org/10.7554/eLife.63589

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