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An External Validation Study of the Oakland and Glasgow-Blatchford Scores for Predicting Adverse Outcomes of Acute Lower Gastrointestinal Bleeding in an Asian Population

AIMS: This study is aimed at (1) validating the performance of Oakland and Glasgow-Blatchford (GBS) scores and (2) comparing these scores with the SALGIB score in predicting adverse outcomes of acute lower gastrointestinal bleeding (ALGIB) in a Vietnamese population. METHODS: A multicenter cohort st...

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Autores principales: Quach, Duc Trong, Vo, Uyen Pham-Phuong, Nguyen, Nguyet Thi-My, Le, Ly Thi-Kim, Vo, Minh-Cong Hong, Ho, Phat Tan, Nguyen, Tran Ngoc, Bo, Phuong Kim, Nguyen, Nam Hoai, Vu, Khanh Truong, Van Dang, Manh, Dinh, Minh Cao, Nguyen, Thai Quang, Van Nguyen, Xung, Le, Suong Thi-Ngoc, Tran, Chi Pham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806364/
https://www.ncbi.nlm.nih.gov/pubmed/33505461
http://dx.doi.org/10.1155/2021/8674367
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author Quach, Duc Trong
Vo, Uyen Pham-Phuong
Nguyen, Nguyet Thi-My
Le, Ly Thi-Kim
Vo, Minh-Cong Hong
Ho, Phat Tan
Nguyen, Tran Ngoc
Bo, Phuong Kim
Nguyen, Nam Hoai
Vu, Khanh Truong
Van Dang, Manh
Dinh, Minh Cao
Nguyen, Thai Quang
Van Nguyen, Xung
Le, Suong Thi-Ngoc
Tran, Chi Pham
author_facet Quach, Duc Trong
Vo, Uyen Pham-Phuong
Nguyen, Nguyet Thi-My
Le, Ly Thi-Kim
Vo, Minh-Cong Hong
Ho, Phat Tan
Nguyen, Tran Ngoc
Bo, Phuong Kim
Nguyen, Nam Hoai
Vu, Khanh Truong
Van Dang, Manh
Dinh, Minh Cao
Nguyen, Thai Quang
Van Nguyen, Xung
Le, Suong Thi-Ngoc
Tran, Chi Pham
author_sort Quach, Duc Trong
collection PubMed
description AIMS: This study is aimed at (1) validating the performance of Oakland and Glasgow-Blatchford (GBS) scores and (2) comparing these scores with the SALGIB score in predicting adverse outcomes of acute lower gastrointestinal bleeding (ALGIB) in a Vietnamese population. METHODS: A multicenter cohort study was conducted on ALGIB patients admitted to seven hospitals across Vietnam. The adverse outcomes of ALGIB consisted of blood transfusion; endoscopic, radiologic, or surgical interventions; severe bleeding; and in-hospital death. The Oakland and GBS scores were calculated, and their performance was compared with that of SALGIB, a locally developed prediction score for adverse outcomes of ALGIB in Vietnamese, based on the data at admission. The accuracy of these scores was measured using the area under the receiver operating characteristic curve (AUC) and compared by the chi-squared test. RESULTS: There were 414 patients with a median age of 60 (48–71). The rates of blood transfusion, hemostatic intervention, severe bleeding, and in-hospital death were 26.8%, 15.2%, 16.4, and 1.4%, respectively. The SALGIB score had comparable performance with the Oakland score (AUC: 0.81 and 0.81, respectively; p = 0.631) and outperformed the GBS score (AUC: 0.81 and 0.76, respectively; p = 0.002) for predicting the presence of any adverse outcomes of ALGIB. All of the three scores had acceptable and comparable performance for in-hospital death but poor performance for hemostatic intervention. The Oakland score had the best performance for predicting severe bleeding. CONCLUSIONS: The Oakland and SALGIB scores had excellent and comparable performance and outperformed the GBS score for predicting adverse outcomes of ALGIB in Vietnamese.
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spelling pubmed-78063642021-01-26 An External Validation Study of the Oakland and Glasgow-Blatchford Scores for Predicting Adverse Outcomes of Acute Lower Gastrointestinal Bleeding in an Asian Population Quach, Duc Trong Vo, Uyen Pham-Phuong Nguyen, Nguyet Thi-My Le, Ly Thi-Kim Vo, Minh-Cong Hong Ho, Phat Tan Nguyen, Tran Ngoc Bo, Phuong Kim Nguyen, Nam Hoai Vu, Khanh Truong Van Dang, Manh Dinh, Minh Cao Nguyen, Thai Quang Van Nguyen, Xung Le, Suong Thi-Ngoc Tran, Chi Pham Gastroenterol Res Pract Research Article AIMS: This study is aimed at (1) validating the performance of Oakland and Glasgow-Blatchford (GBS) scores and (2) comparing these scores with the SALGIB score in predicting adverse outcomes of acute lower gastrointestinal bleeding (ALGIB) in a Vietnamese population. METHODS: A multicenter cohort study was conducted on ALGIB patients admitted to seven hospitals across Vietnam. The adverse outcomes of ALGIB consisted of blood transfusion; endoscopic, radiologic, or surgical interventions; severe bleeding; and in-hospital death. The Oakland and GBS scores were calculated, and their performance was compared with that of SALGIB, a locally developed prediction score for adverse outcomes of ALGIB in Vietnamese, based on the data at admission. The accuracy of these scores was measured using the area under the receiver operating characteristic curve (AUC) and compared by the chi-squared test. RESULTS: There were 414 patients with a median age of 60 (48–71). The rates of blood transfusion, hemostatic intervention, severe bleeding, and in-hospital death were 26.8%, 15.2%, 16.4, and 1.4%, respectively. The SALGIB score had comparable performance with the Oakland score (AUC: 0.81 and 0.81, respectively; p = 0.631) and outperformed the GBS score (AUC: 0.81 and 0.76, respectively; p = 0.002) for predicting the presence of any adverse outcomes of ALGIB. All of the three scores had acceptable and comparable performance for in-hospital death but poor performance for hemostatic intervention. The Oakland score had the best performance for predicting severe bleeding. CONCLUSIONS: The Oakland and SALGIB scores had excellent and comparable performance and outperformed the GBS score for predicting adverse outcomes of ALGIB in Vietnamese. Hindawi 2021-01-05 /pmc/articles/PMC7806364/ /pubmed/33505461 http://dx.doi.org/10.1155/2021/8674367 Text en Copyright © 2021 Duc Trong Quach et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Quach, Duc Trong
Vo, Uyen Pham-Phuong
Nguyen, Nguyet Thi-My
Le, Ly Thi-Kim
Vo, Minh-Cong Hong
Ho, Phat Tan
Nguyen, Tran Ngoc
Bo, Phuong Kim
Nguyen, Nam Hoai
Vu, Khanh Truong
Van Dang, Manh
Dinh, Minh Cao
Nguyen, Thai Quang
Van Nguyen, Xung
Le, Suong Thi-Ngoc
Tran, Chi Pham
An External Validation Study of the Oakland and Glasgow-Blatchford Scores for Predicting Adverse Outcomes of Acute Lower Gastrointestinal Bleeding in an Asian Population
title An External Validation Study of the Oakland and Glasgow-Blatchford Scores for Predicting Adverse Outcomes of Acute Lower Gastrointestinal Bleeding in an Asian Population
title_full An External Validation Study of the Oakland and Glasgow-Blatchford Scores for Predicting Adverse Outcomes of Acute Lower Gastrointestinal Bleeding in an Asian Population
title_fullStr An External Validation Study of the Oakland and Glasgow-Blatchford Scores for Predicting Adverse Outcomes of Acute Lower Gastrointestinal Bleeding in an Asian Population
title_full_unstemmed An External Validation Study of the Oakland and Glasgow-Blatchford Scores for Predicting Adverse Outcomes of Acute Lower Gastrointestinal Bleeding in an Asian Population
title_short An External Validation Study of the Oakland and Glasgow-Blatchford Scores for Predicting Adverse Outcomes of Acute Lower Gastrointestinal Bleeding in an Asian Population
title_sort external validation study of the oakland and glasgow-blatchford scores for predicting adverse outcomes of acute lower gastrointestinal bleeding in an asian population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806364/
https://www.ncbi.nlm.nih.gov/pubmed/33505461
http://dx.doi.org/10.1155/2021/8674367
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