Cargando…

Electroacupuncture Ameliorates Neuroinflammation-Mediated Cognitive Deficits through Inhibition of NLRP3 in Presenilin1/2 Conditional Double Knockout Mice

Neuroinflammation is considered as one of the crucial pathogenesis in promoting neurodegenerative progress of Alzheimer's disease (AD). As complementary and alternative therapy, electroacupuncture (EA) stimulation has been widely used in clinical practice for anti-inflammation. However, whether...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Kun, Shi, Guoqi, Zhao, Yang, Chen, Yiwen, Gao, Jie, Yao, Lin, Zhao, Jiaying, Li, Hongzhu, Xu, Ying, Chen, Yongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806385/ https://www.ncbi.nlm.nih.gov/pubmed/33505459 http://dx.doi.org/10.1155/2021/8814616

Ejemplares similares

Effects of electroacupuncture on urinary metabolome and microbiota in presenilin1/2 conditional double knockout mice
por: Gao, Jie, et al.
Publicado: (2023)

Spatiotemporal patterns of gliosis and neuroinflammation in presenilin 1/2 conditional double knockout mice
por: Peng, Wenjun, et al.
Publicado: (2022)

Guizhi Fuling capsule relieves memory deficits by inhibition of microglial neuroinflammation through blocking JAK2/STAT3 pathway in presenilin1/2 conditional double knockout mice
por: Yang, Guang, et al.
Publicado: (2023)

Ibuprofen Rescues Abnormalities in Periodontal Tissues in Conditional Presenilin 1 and Presenilin 2 Double Knockout Mice
por: Su, Jiansheng, et al.
Publicado: (2013)

Electroacupuncture ameliorates postoperative cognitive dysfunction and associated neuroinflammation via NLRP3 signal inhibition in aged mice
por: Sun, Long, et al.
Publicado: (2021)

Early electroacupuncture treatment ameliorates neuroinflammation in rats with traumatic brain injury
por: Tang, Wei-Chen, et al.
Publicado: (2016)

Electroacupuncture ameliorates surgery-induced spatial memory deficits by promoting mitophagy in rats
por: Guo, Jian, et al.
Publicado: (2023)

Urinary metabolomic changes and microbiotic alterations in presenilin1/2 conditional double knockout mice
por: Gao, Jie, et al.
Publicado: (2021)

Electroacupuncture Ameliorates Cognitive Deficit and Improves Hippocampal Synaptic Plasticity in Adult Rat with Neonatal Maternal Separation
por: Guo, Lili, et al.
Publicado: (2018)

Electroacupuncture Ameliorates Acute Myocardial Ischemia: A Potential Role of the Locus Coeruleus
por: Wu, Xin, et al.
Publicado: (2020)

Electroacupuncture ameliorates knee osteoarthritis in rats via inhibiting NLRP3 inflammasome and reducing pyroptosis
por: Zhang, Wei, et al.
Publicado: (2023)

Dihydroquercetin ameliorates LPS-induced neuroinflammation and memory deficit
por: Alam, Qadir, et al.
Publicado: (2022)

Inhibition of NLRP3 and Golph3 ameliorates diabetes-induced neuroinflammation in vitro and in vivo
por: Li, Yuan, et al.
Publicado: (2022)

The presenilins
por: Tandon, Anurag, et al.
Publicado: (2002)

DI-3-n-butylphthalide mitigates stress-induced cognitive deficits in mice through inhibition of NLRP3-Mediated neuroinflammation
por: Chen, Xiu, et al.
Publicado: (2022)

Pioglitazone ameliorates glomerular NLRP3 inflammasome activation in apolipoprotein E knockout mice with diabetes mellitus
por: Wang, Yao, et al.
Publicado: (2017)

Electroacupuncture Alleviates Osteoarthritis by Suppressing NLRP3 Inflammasome Activation in Guinea Pigs
por: Wang, Zhankui, et al.
Publicado: (2020)

Transcriptome Analysis on Maternal Separation Rats With Depression-Related Manifestations Ameliorated by Electroacupuncture
por: Zheng, Yuanjia, et al.
Publicado: (2019)

Berberine ameliorates depression-like behaviors in mice via inhibiting NLRP3 inflammasome-mediated neuroinflammation and preventing neuroplasticity disruption
por: Qin, Zongshi, et al.
Publicado: (2023)

Unraveling Presenilin 2 Functions in a Knockout Zebrafish Line to Shed Light into Alzheimer’s Disease Pathogenesis
por: Barazzuol, Lucia, et al.
Publicado: (2023)

Adult hippocampal neurogenesis occurs in the absence of Presenilin 1 and Presenilin 2
por: Dhaliwal, Jagroop, et al.
Publicado: (2018)

Structure and dynamics of γ-secretase with presenilin 2 compared to presenilin 1
por: Dehury, Budheswar, et al.
Publicado: (2019)

A20-Binding Inhibitor of NF-κB 1 Ameliorates Neuroinflammation and Mediates Antineuroinflammatory Effect of Electroacupuncture in Cerebral Ischemia/Reperfusion Rats
por: Zhou, Xueling, et al.
Publicado: (2020)

Electroacupuncture Ameliorates Cerebral Ischemic Injury by Inhibiting Ferroptosis
por: Li, Guangda, et al.
Publicado: (2021)

Neuregulin1-ErbB4 Signaling in Spinal Cord Participates in Electroacupuncture Analgesia in Inflammatory Pain
por: Wan, Chaofan, et al.
Publicado: (2021)

Structural biology of presenilin 1 complexes
por: Li, Yi, et al.
Publicado: (2014)

Electroacupuncture attenuated cerebral ischemic injury and neuroinflammation through α7nAChR-mediated inhibition of NLRP3 inflammasome in stroke rats
por: Jiang, Tao, et al.
Publicado: (2019)

Electroacupuncture Ameliorates the Coronary Occlusion Related Tachycardia and Hypotension in Acute Rat Myocardial Ischemia Model: Potential Role of Hippocampus
por: Wu, Shengbing, et al.
Publicado: (2015)

Electroacupuncture at ST 36 ameliorates cognitive impairment and beta-amyloid pathology by inhibiting NLRP3 inflammasome activation in an Alzheimer’s disease animal model
por: Ni, Hong, et al.
Publicado: (2023)

Vitamin A Deficiency Exacerbates Gut Microbiota Dysbiosis and Cognitive Deficits in Amyloid Precursor Protein/Presenilin 1 Transgenic Mice
por: Chen, Bo-Wen, et al.
Publicado: (2021)

Identification of Ubiquilin, a Novel Presenilin Interactor That Increases Presenilin Protein Accumulation
por: Mah, Alex L., et al.
Publicado: (2000)

Electroacupuncture ameliorating post-stroke cognitive impairments via inhibition of peri-infarct astroglial and microglial/macrophage P2 purinoceptors-mediated neuroinflammation and hyperplasia
por: Huang, Jia, et al.
Publicado: (2017)

Deficits of learning and memory in Hemojuvelin knockout mice
por: LI, Jinglong, et al.
Publicado: (2015)

Early Contextual Fear Memory Deficits in a Double-Transgenic Amyloid-β Precursor Protein/Presenilin 2 Mouse Model of Alzheimer's Disease
por: Kishimoto, Yasushi, et al.
Publicado: (2017)

Electroacupuncture at Fengchi(GB20) and Yanglingquan(GB34) Ameliorates Paralgesia through Microglia-Mediated Neuroinflammation in a Rat Model of Migraine
por: Zhou, Min, et al.
Publicado: (2023)

Electroacupuncture of Baihui and Shenting ameliorates cognitive deficits via Pten/Akt pathway in a rat cerebral ischemia injury model
por: Su, Kaiqi, et al.
Publicado: (2022)

Electroacupuncture Ameliorates Mechanical Allodynia of a Rat Model of CRPS-I via Suppressing NLRP3 Inflammasome Activation in Spinal Cord Dorsal Horn Neurons
por: Zhang, Yunwen, et al.
Publicado: (2022)

Intracellular Calcium Deficits in Drosophila Cholinergic Neurons Expressing Wild Type or FAD-Mutant Presenilin
por: Michno, Kinga, et al.
Publicado: (2009)

Specificity of presenilin‐1‐ and presenilin‐2‐dependent γ‐secretases towards substrate processing
por: Stanga, Serena, et al.
Publicado: (2017)

Glucose-Dependent Insulinotropic Polypeptide Ameliorates Mild Traumatic Brain Injury-Induced Cognitive and Sensorimotor Deficits and Neuroinflammation in Rats
por: Yu, Yu-Wen, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jcfb3m09j1m9p88hqeu7gqj687