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Metformin-Induced MicroRNA-34a-3p Downregulation Alleviates Senescence in Human Dental Pulp Stem Cells by Targeting CAB39 through the AMPK/mTOR Signaling Pathway

Dental pulp stem cells (DPSCs) are ideal seed cells for the regeneration of dental tissues. However, DPSC senescence restricts its clinical applications. Metformin (Met), a common prescription drug for type 2 diabetes, is thought to influence the aging process. This study is aimed at determining the...

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Detalles Bibliográficos
Autores principales:	Zhang, Shuo, Zhang, Rong, Qiao, Pengyan, Ma, Xiaocao, Lu, Rongjian, Wang, Feifan, Li, Chuanjie, E, Lingling, Liu, Hongchen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806386/ https://www.ncbi.nlm.nih.gov/pubmed/33505470 http://dx.doi.org/10.1155/2021/6616240

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