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Factors Associated with Medication Adherence for People Living with Acute HIV Infection in a Tertiary Chinese Hospital in Beijing

Both the management and caregiving intervention of people living with HIV (PLWH), especially during acute HIV-1 infection, represent a public health issue and a form of social support. This current study analyzed the demographic and clinical factors associated with antiretroviral therapy (ART) adher...

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Autores principales: Wang, Xiaolan, Li, Dongmei, Gao, Meixia, Zhou, Yuefang, Guo, Caiping, Zhang, Tong, Zhang, Lili, Wang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806394/
https://www.ncbi.nlm.nih.gov/pubmed/33506008
http://dx.doi.org/10.1155/2021/1078716
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author Wang, Xiaolan
Li, Dongmei
Gao, Meixia
Zhou, Yuefang
Guo, Caiping
Zhang, Tong
Zhang, Lili
Wang, Wen
author_facet Wang, Xiaolan
Li, Dongmei
Gao, Meixia
Zhou, Yuefang
Guo, Caiping
Zhang, Tong
Zhang, Lili
Wang, Wen
author_sort Wang, Xiaolan
collection PubMed
description Both the management and caregiving intervention of people living with HIV (PLWH), especially during acute HIV-1 infection, represent a public health issue and a form of social support. This current study analyzed the demographic and clinical factors associated with antiretroviral therapy (ART) adherence of PLWH from positive HIV diagnosis to ART initiation in a tertiary Chinese hospital in Beijing. A total of 200 participants diagnosed with acute HIV-1 infection were enrolled in this study. We collected demographic and clinical data by the use of a self-reported questionnaire. Bivariate and multivariate logistic regressions were used to determine associations between potential variables and outcomes. We found that medication adherence was impacted by years of ART and number of reminders (all P < 0.05). In addition, medication adherence was associated with viral load at 48 weeks (P = 0.035). Future studies are needed to investigate effective interventions that could facilitate ART adherence.
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spelling pubmed-78063942021-01-26 Factors Associated with Medication Adherence for People Living with Acute HIV Infection in a Tertiary Chinese Hospital in Beijing Wang, Xiaolan Li, Dongmei Gao, Meixia Zhou, Yuefang Guo, Caiping Zhang, Tong Zhang, Lili Wang, Wen Biomed Res Int Research Article Both the management and caregiving intervention of people living with HIV (PLWH), especially during acute HIV-1 infection, represent a public health issue and a form of social support. This current study analyzed the demographic and clinical factors associated with antiretroviral therapy (ART) adherence of PLWH from positive HIV diagnosis to ART initiation in a tertiary Chinese hospital in Beijing. A total of 200 participants diagnosed with acute HIV-1 infection were enrolled in this study. We collected demographic and clinical data by the use of a self-reported questionnaire. Bivariate and multivariate logistic regressions were used to determine associations between potential variables and outcomes. We found that medication adherence was impacted by years of ART and number of reminders (all P < 0.05). In addition, medication adherence was associated with viral load at 48 weeks (P = 0.035). Future studies are needed to investigate effective interventions that could facilitate ART adherence. Hindawi 2021-01-05 /pmc/articles/PMC7806394/ /pubmed/33506008 http://dx.doi.org/10.1155/2021/1078716 Text en Copyright © 2021 Xiaolan Wang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Xiaolan
Li, Dongmei
Gao, Meixia
Zhou, Yuefang
Guo, Caiping
Zhang, Tong
Zhang, Lili
Wang, Wen
Factors Associated with Medication Adherence for People Living with Acute HIV Infection in a Tertiary Chinese Hospital in Beijing
title Factors Associated with Medication Adherence for People Living with Acute HIV Infection in a Tertiary Chinese Hospital in Beijing
title_full Factors Associated with Medication Adherence for People Living with Acute HIV Infection in a Tertiary Chinese Hospital in Beijing
title_fullStr Factors Associated with Medication Adherence for People Living with Acute HIV Infection in a Tertiary Chinese Hospital in Beijing
title_full_unstemmed Factors Associated with Medication Adherence for People Living with Acute HIV Infection in a Tertiary Chinese Hospital in Beijing
title_short Factors Associated with Medication Adherence for People Living with Acute HIV Infection in a Tertiary Chinese Hospital in Beijing
title_sort factors associated with medication adherence for people living with acute hiv infection in a tertiary chinese hospital in beijing
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806394/
https://www.ncbi.nlm.nih.gov/pubmed/33506008
http://dx.doi.org/10.1155/2021/1078716
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