Blockade of deubiquitinating enzyme PSMD14 overcomes chemoresistance in head and neck squamous cell carcinoma by antagonizing E2F1/Akt/SOX2-mediated stemness

Increasing evidence reveals a close relationship between deubiquitinating enzymes (DUBs) and cancer progression. In this study, we attempted to identify the roles and mechanisms of critical DUBs in head and neck squamous cell carcinoma (HNSCC). Methods: Bioinformatics analysis was performed to scree...

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Detalles Bibliográficos
Autores principales: Jing, Chao, Duan, Yuansheng, Zhou, Mengqian, Yue, Kai, Zhuo, Shanshan, Li, Xingchen, Liu, Dandan, Ye, Beibei, Lai, Qingchuan, Li, Linqi, Yao, Xiaofeng, Wei, Hui, Zhang, Wenchao, Wu, Yansheng, Wang, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806466/
https://www.ncbi.nlm.nih.gov/pubmed/33456565
http://dx.doi.org/10.7150/thno.48375

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