Cisplatin-resistant NSCLC cells induced by hypoxia transmit resistance to sensitive cells through exosomal PKM2

Hypoxia is commonly observed in solid tumors and contributes to the resistance of DNA damage drugs. However, the mechanisms behind this resistance are still unclear. In this study, we aimed to explore the effects of hypoxia-induced exosomes on non-small cell lung cancer (NSCLC). Methods: NSCLC cells...

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Detalles Bibliográficos
Autores principales: Wang, Dongliang, Zhao, Chaoshuai, Xu, Fei, Zhang, Aimi, Jin, Mingming, Zhang, Kunchi, Liu, Liu, Hua, Qian, Zhao, Jian, Liu, Jianjun, Yang, Hao, Huang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806469/
https://www.ncbi.nlm.nih.gov/pubmed/33456577
http://dx.doi.org/10.7150/thno.51797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806469/
https://www.ncbi.nlm.nih.gov/pubmed/33456577
http://dx.doi.org/10.7150/thno.51797

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