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Cisplatin-resistant NSCLC cells induced by hypoxia transmit resistance to sensitive cells through exosomal PKM2
Hypoxia is commonly observed in solid tumors and contributes to the resistance of DNA damage drugs. However, the mechanisms behind this resistance are still unclear. In this study, we aimed to explore the effects of hypoxia-induced exosomes on non-small cell lung cancer (NSCLC). Methods: NSCLC cells...
Autores principales: | Wang, Dongliang, Zhao, Chaoshuai, Xu, Fei, Zhang, Aimi, Jin, Mingming, Zhang, Kunchi, Liu, Liu, Hua, Qian, Zhao, Jian, Liu, Jianjun, Yang, Hao, Huang, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806469/ https://www.ncbi.nlm.nih.gov/pubmed/33456577 http://dx.doi.org/10.7150/thno.51797 |
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