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Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein

Interactions between the hepatitis B virus core protein (HBc) and host cell proteins are poorly understood, although they may be essential for the propagation of the virus and its pathogenicity. HBc has a C-terminal PDZ (PSD-95, Dlg1, ZO-1)-binding motif (PBM) that is responsible for interactions wi...

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Detalles Bibliográficos
Autores principales: Genera, Mariano, Quioc-Salomon, Barbara, Nourisson, Antonin, Colcombet-Cazenave, Baptiste, Haouz, Ahmed, Mechaly, Ariel, Matondo, Mariette, Duchateau, Magalie, König, Alexander, Windisch, Marc P., Neuveut, Christine, Wolff, Nicolas, Caillet-Saguy, Célia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806630/
https://www.ncbi.nlm.nih.gov/pubmed/33441627
http://dx.doi.org/10.1038/s41598-020-79580-9