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The mitochondrial permeability transition phenomenon elucidated by cryo-EM reveals the genuine impact of calcium overload on mitochondrial structure and function
Mitochondria have a remarkable ability to uptake and store massive amounts of calcium. However, the consequences of massive calcium accumulation remain enigmatic. In the present study, we analyzed a series of time-course experiments to identify the sequence of events that occur in a population of gu...
Autores principales: | Strubbe-Rivera, Jasiel O., Schrad, Jason R., Pavlov, Evgeny V., Conway, James F., Parent, Kristin N., Bazil, Jason N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806632/ https://www.ncbi.nlm.nih.gov/pubmed/33441863 http://dx.doi.org/10.1038/s41598-020-80398-8 |
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