Cargando…
Restoration of the reduced CLSP activity alleviates memory impairment in Alzheimer disease
Calmodulin-like skin protein (CLSP), a secreted peptide, inhibits neuronal death in cell-based Alzheimer’s disease (AD) models and transgenic overexpression of the CLSP gene suppresses synaptic loss and memory impairment in AD model mice, APPswe/PS1dE9 double transgenic mice (APP/PS1 mice). Despite...
Autores principales: | Hashimoto, Yuichi, Kusakari, Shinya, Nawa, Mikiro, Okamoto, Koichi, Toyama, Yuka, Matsuoka, Masaaki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806720/ https://www.ncbi.nlm.nih.gov/pubmed/33441550 http://dx.doi.org/10.1038/s41398-020-01168-8 |
Ejemplares similares
-
CLSPCOL rescues Alzheimer’s disease mouse models
por: Kusakari, Shinya, et al.
Publicado: (2022) -
KCTD20, a relative of BTBD10, is a positive regulator of Akt
por: Nawa, Mikiro, et al.
Publicado: (2013) -
A Critical Role for CLSP2 in the Modulation of Antifungal Immune Response in Mosquitoes
por: Wang, Yan-Hong, et al.
Publicado: (2015) -
Restoration of Calmodulin-Like Skin Protein as Treatment for Alzheimer's Disease
por: Matsuoka, Masaaki
Publicado: (2021) -
Structure and Cleavage Specificity of the Chymotrypsin-Like Serine Protease (3CLSP/nsp4) of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
por: Tian, Xinsheng, et al.
Publicado: (2009)