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Ellagic acid and its fermentative derivative urolithin A show reverse effects on the gp91-phox gene expression, resulting in opposite alterations in all-trans retinoic acid-induced superoxide generating activity of U937 cells

Ellagitannins (esters composed of glucose and ellagic acid) are hydrolyzed to generate ellagic acid in gut followed by conversion of ellagic acid to urolithins such as urolithin A by intestinal bacteria. Since urolithins are absorbed by gut easier than ellagitannins and ellagic acid, and show variou...

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Detalles Bibliográficos
Autores principales: Kikuchi, Hidehiko, Harata, Kaori, Madhyastha, Harishkumar, Kuribayashi, Futoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806786/
https://www.ncbi.nlm.nih.gov/pubmed/33490645
http://dx.doi.org/10.1016/j.bbrep.2020.100891

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