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Increasing neuronal glucose uptake attenuates brain aging and promotes life span under dietary restriction in Drosophila

Brain neurons play a central role in organismal aging, but there is conflicting evidence about the role of neuronal glucose availability because glucose uptake and metabolism are associated with both aging and extended life span. Here, we analyzed metabolic changes in the brain neurons of Drosophila...

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Detalles Bibliográficos
Autores principales: Oka, Mikiko, Suzuki, Emiko, Asada, Akiko, Saito, Taro, Iijima, Koichi M., Ando, Kanae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806808/
https://www.ncbi.nlm.nih.gov/pubmed/33490892
http://dx.doi.org/10.1016/j.isci.2020.101979