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Regulation of carcinogenesis and mediation through Wnt/β-catenin signaling by 3,3′-diindolylmethane in an enzalutamide-resistant prostate cancer cell line

Enzalutamide (ENZ) is an important drug used to treat castration-resistant prostate cancer (CRPC), which inhibits androgen receptor (AR) signaling. Previous study showed that 3,3′-diindolylmethane (DIM) is an AR antagonist that also inhibits Wnt signaling and epithelial-mesenchymal transition (EMT)....

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Detalles Bibliográficos
Autores principales:	Tsao, Chih-Wei, Li, Jia-Sin, Lin, Ya-Wen, Wu, Sheng-Tang, Cha, Tai-Lung, Liu, Chin-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806813/ https://www.ncbi.nlm.nih.gov/pubmed/33441906 http://dx.doi.org/10.1038/s41598-020-80519-3

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