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Tristetraprolin Promotes Hepatic Inflammation and Tumor Initiation but Restrains Cancer Progression to Malignancy

BACKGROUND & AIMS: Tristetraprolin (TTP) is a key post-transcriptional regulator of inflammatory and oncogenic transcripts. Accordingly, TTP was reported to act as a tumor suppressor in specific cancers. Herein, we investigated how TTP contributes to the development of liver inflammation and fib...

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Detalles Bibliográficos
Autores principales: Dolicka, Dobrochna, Sobolewski, Cyril, Gjorgjieva, Monika, Correia de Sousa, Marta, Berthou, Flavien, De Vito, Claudio, Colin, Didier J., Bejuy, Olivia, Fournier, Margot, Maeder, Christine, Blackshear, Perry J., Rubbia-Brandt, Laura, Foti, Michelangelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806869/
https://www.ncbi.nlm.nih.gov/pubmed/32987153
http://dx.doi.org/10.1016/j.jcmgh.2020.09.012