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High expression of hypoxia inducible factor 1α related with acquired resistant to EGFR tyrosine kinase inhibitors in NSCLC

The acquired resistance of the first generation epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) is a main factor leading to poor prognosis of non-small cell lung cancer (NSCLC), so we researched whether the high expression of hypoxia-inducible factor-1α (HIF-1α) in EGFR-TKIs...

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Detalles Bibliográficos
Autores principales:	Jin, Qian, Huang, Feihua, Xu, Xianrong, He, Haidong, Zhang, Yingqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806909/ https://www.ncbi.nlm.nih.gov/pubmed/33441708 http://dx.doi.org/10.1038/s41598-020-79801-1

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