MicroRNA-494-3p inhibits formation of fast oxidative muscle fibres by targeting E1A-binding protein p300 in human-induced pluripotent stem cells

MYOD-induced microRNA-494-3p expression inhibits fast oxidative myotube formation by downregulating myosin heavy chain 2 (MYH2) in human induced pluripotent stem cells (hiPSCs) during skeletal myogenesis. However, the molecular mechanisms regulating MYH2 expression via miR-494-3p remain unknown. Her...

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Detalles Bibliográficos
Autores principales: Iwasaki, Hirotaka, Ichihara, Yoshinori, Morino, Katsutaro, Lemecha, Mengistu, Sugawara, Lucia, Sawano, Tatsuya, Miake, Junichiro, Sakurai, Hidetoshi, Nishi, Eiichiro, Maegawa, Hiroshi, Imamura, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806978/
https://www.ncbi.nlm.nih.gov/pubmed/33441918
http://dx.doi.org/10.1038/s41598-020-80742-y

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