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Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo

Burkholderia cenocepacia (B. cenocepacia) is an opportunistic bacterium; causing severe life threatening systemic infections in immunocompromised individuals including cystic fibrosis patients. The lack of gasdermin D (GSDMD) protects mice against endotoxin lipopolysaccharide (LPS) shock. On the oth...

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Detalles Bibliográficos
Autores principales: Estfanous, Shady, Krause, Kathrin, Anne, Midhun N. K., Eltobgy, Mostafa, Caution, Kyle, Abu Khweek, Arwa, Hamilton, Kaitlin, Badr, Asmaa, Daily, Kylene, Carafice, Cierra, Baetzhold, Daniel, Zhang, Xiaoli, Li, Tianliang, Wen, Haitao, Gavrilin, Mikhail A., Haffez, Hesham, Soror, Sameh, Amer, Amal O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807041/
https://www.ncbi.nlm.nih.gov/pubmed/33441602
http://dx.doi.org/10.1038/s41598-020-79201-5