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A combination of CMC and α-MSH inhibited ROS activated NLRP3 inflammasome in hyperosmolarity stressed HCECs and scopolamine-induced dry eye rats

An important mechanism involved in dry eye (DE) is the association between tear hyperosmolarity and inflammation severity. Inflammation in DE might be mediated by the NLRP3 inflammasome, which activated by exposure to reactive oxygen species (ROS). A combination of carboxymethylcellulose (CMC) and α...

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Detalles Bibliográficos
Autores principales:	Lv, Ying, Chu, Chenchen, Liu, Ke, Ru, Yusha, Zhang, Yan, Lu, Xiaoxiao, Gao, Yichen, Zhang, Caijie, Zhao, Shaozhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807058/ https://www.ncbi.nlm.nih.gov/pubmed/33441928 http://dx.doi.org/10.1038/s41598-020-80849-2

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