Isolated Cerebral Vasculitis in the Unilateral Middle Cerebral Artery in a Case with SLE

A 47-year-old woman, who was diagnosed to have systemic lupus erythematosus (SLE), was admitted because she suffered a severe ischemic stroke three weeks after experiencing a transient attack of aphasia. Diffusion-weighted MRI revealed high intensity at the borderzone of the middle cerebral artery (...

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Autores principales: Takeshita, Sho, Ogata, Toshiyasu, Tsugawa, Jun, Tsuboi, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807120/
https://www.ncbi.nlm.nih.gov/pubmed/32713917
http://dx.doi.org/10.2169/internalmedicine.4958-20
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author Takeshita, Sho
Ogata, Toshiyasu
Tsugawa, Jun
Tsuboi, Yoshio
author_facet Takeshita, Sho
Ogata, Toshiyasu
Tsugawa, Jun
Tsuboi, Yoshio
author_sort Takeshita, Sho
collection PubMed
description A 47-year-old woman, who was diagnosed to have systemic lupus erythematosus (SLE), was admitted because she suffered a severe ischemic stroke three weeks after experiencing a transient attack of aphasia. Diffusion-weighted MRI revealed high intensity at the borderzone of the middle cerebral artery (MCA), while the proximal portion of the left MCA was occluded with its vascular wall enhanced by gadolinium. Intravenous methylprednisolone and heparin were administrated without any symptomatic benefit. She developed severe right hemiparesis with aphasia. Isolated cerebral vasculitis in the large vessel has been rarely reported in SLE patients. The presence of an enhanced vascular wall in the MRI with gadolinium could support the diagnosis.
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spelling pubmed-78071202021-01-27 Isolated Cerebral Vasculitis in the Unilateral Middle Cerebral Artery in a Case with SLE Takeshita, Sho Ogata, Toshiyasu Tsugawa, Jun Tsuboi, Yoshio Intern Med Case Report A 47-year-old woman, who was diagnosed to have systemic lupus erythematosus (SLE), was admitted because she suffered a severe ischemic stroke three weeks after experiencing a transient attack of aphasia. Diffusion-weighted MRI revealed high intensity at the borderzone of the middle cerebral artery (MCA), while the proximal portion of the left MCA was occluded with its vascular wall enhanced by gadolinium. Intravenous methylprednisolone and heparin were administrated without any symptomatic benefit. She developed severe right hemiparesis with aphasia. Isolated cerebral vasculitis in the large vessel has been rarely reported in SLE patients. The presence of an enhanced vascular wall in the MRI with gadolinium could support the diagnosis. The Japanese Society of Internal Medicine 2020-07-21 2020-12-15 /pmc/articles/PMC7807120/ /pubmed/32713917 http://dx.doi.org/10.2169/internalmedicine.4958-20 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Takeshita, Sho
Ogata, Toshiyasu
Tsugawa, Jun
Tsuboi, Yoshio
Isolated Cerebral Vasculitis in the Unilateral Middle Cerebral Artery in a Case with SLE
title Isolated Cerebral Vasculitis in the Unilateral Middle Cerebral Artery in a Case with SLE
title_full Isolated Cerebral Vasculitis in the Unilateral Middle Cerebral Artery in a Case with SLE
title_fullStr Isolated Cerebral Vasculitis in the Unilateral Middle Cerebral Artery in a Case with SLE
title_full_unstemmed Isolated Cerebral Vasculitis in the Unilateral Middle Cerebral Artery in a Case with SLE
title_short Isolated Cerebral Vasculitis in the Unilateral Middle Cerebral Artery in a Case with SLE
title_sort isolated cerebral vasculitis in the unilateral middle cerebral artery in a case with sle
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807120/
https://www.ncbi.nlm.nih.gov/pubmed/32713917
http://dx.doi.org/10.2169/internalmedicine.4958-20
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