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Brd2/4 and Myc regulate alternative cell lineage programmes during early osteoclast differentiation in vitro

Osteoclast (OC) development in response to nuclear factor kappa-Β ligand (RANKL) is critical for bone homeostasis in health and in disease. The early and direct chromatin regulatory changes imparted by the BET chromatin readers Brd2-4 and OC-affiliated transcription factors (TFs) during osteoclastog...

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Detalles Bibliográficos
Autores principales: Caputo, Valentina S., Trasanidis, Nikolaos, Xiao, Xiaolin, Robinson, Mark E., Katsarou, Alexia, Ponnusamy, Kanagaraju, Prinjha, Rab K., Smithers, Nicholas, Chaidos, Aristeidis, Auner, Holger W., Karadimitris, Anastasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807155/
https://www.ncbi.nlm.nih.gov/pubmed/33490899
http://dx.doi.org/10.1016/j.isci.2020.101989

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