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Brd2/4 and Myc regulate alternative cell lineage programmes during early osteoclast differentiation in vitro
Osteoclast (OC) development in response to nuclear factor kappa-Β ligand (RANKL) is critical for bone homeostasis in health and in disease. The early and direct chromatin regulatory changes imparted by the BET chromatin readers Brd2-4 and OC-affiliated transcription factors (TFs) during osteoclastog...
Autores principales: | Caputo, Valentina S., Trasanidis, Nikolaos, Xiao, Xiaolin, Robinson, Mark E., Katsarou, Alexia, Ponnusamy, Kanagaraju, Prinjha, Rab K., Smithers, Nicholas, Chaidos, Aristeidis, Auner, Holger W., Karadimitris, Anastasios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807155/ https://www.ncbi.nlm.nih.gov/pubmed/33490899 http://dx.doi.org/10.1016/j.isci.2020.101989 |
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