Cargando…

Postnatal Arx transcriptional activity regulates functional properties of PV interneurons

The transcription factor Aristaless-related X-linked gene (Arx) is a monogenic factor in early onset epileptic encephalopathies (EOEEs) and a fundamental regulator of early stages of brain development. However, Arx expression persists in mature GABAergic neurons with an unknown role. To address this...

Descripción completa

Detalles Bibliográficos
Autores principales: Joseph, Donald J., Von Deimling, Markus, Hasegawa, Yuiko, Cristancho, Ana G., Ahrens-Nicklas, Rebecca C., Rogers, Stephanie L., Risbud, Rashmi, McCoy, Almedia J., Marsh, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807163/
https://www.ncbi.nlm.nih.gov/pubmed/33490907
http://dx.doi.org/10.1016/j.isci.2020.101999