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Inguinal lymph node dissection for penile cancer: a contemporary review

Penile cancer is an uncommon disease associated with significant psychological and physical morbidity. Penile cancer has an expectable pattern of spread in a stepwise fashion, from inguinal to pelvic lymph nodes (PLN) then distant spread. Patients with penile cancer have variable survival, with pati...

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Autores principales: Teh, Jiasian, Duncan, Catriona, Qu, Liang, Guerra, Glen, Narasimhan, Vignesh, Pham, Toan, Lawrentschuk, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807325/
https://www.ncbi.nlm.nih.gov/pubmed/33457292
http://dx.doi.org/10.21037/tau.2019.08.37
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author Teh, Jiasian
Duncan, Catriona
Qu, Liang
Guerra, Glen
Narasimhan, Vignesh
Pham, Toan
Lawrentschuk, Nathan
author_facet Teh, Jiasian
Duncan, Catriona
Qu, Liang
Guerra, Glen
Narasimhan, Vignesh
Pham, Toan
Lawrentschuk, Nathan
author_sort Teh, Jiasian
collection PubMed
description Penile cancer is an uncommon disease associated with significant psychological and physical morbidity. Penile cancer has an expectable pattern of spread in a stepwise fashion, from inguinal to pelvic lymph nodes (PLN) then distant spread. Patients with penile cancer have variable survival, with patients with a low burden of nodal metastatic disease having lasting survival with surgical management, however patients with a large amount of locoregional metastatic disease having a worse prognosis. The current management options for patients with metastatic lymph node disease in penile cancer aims to reduce the morbidity associated with radical inguinal lymph node (ILN) surgery with appropriate risk stratification to optimise oncological control of the disease. This article describes current challenges in managing the inguinal region in patients with penile squamous cell carcinoma (SCC).
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spelling pubmed-78073252021-01-15 Inguinal lymph node dissection for penile cancer: a contemporary review Teh, Jiasian Duncan, Catriona Qu, Liang Guerra, Glen Narasimhan, Vignesh Pham, Toan Lawrentschuk, Nathan Transl Androl Urol Review Article on Surgery for Urologic Cancers Penile cancer is an uncommon disease associated with significant psychological and physical morbidity. Penile cancer has an expectable pattern of spread in a stepwise fashion, from inguinal to pelvic lymph nodes (PLN) then distant spread. Patients with penile cancer have variable survival, with patients with a low burden of nodal metastatic disease having lasting survival with surgical management, however patients with a large amount of locoregional metastatic disease having a worse prognosis. The current management options for patients with metastatic lymph node disease in penile cancer aims to reduce the morbidity associated with radical inguinal lymph node (ILN) surgery with appropriate risk stratification to optimise oncological control of the disease. This article describes current challenges in managing the inguinal region in patients with penile squamous cell carcinoma (SCC). AME Publishing Company 2020-12 /pmc/articles/PMC7807325/ /pubmed/33457292 http://dx.doi.org/10.21037/tau.2019.08.37 Text en 2020 Translational Andrology and Urology. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review Article on Surgery for Urologic Cancers
Teh, Jiasian
Duncan, Catriona
Qu, Liang
Guerra, Glen
Narasimhan, Vignesh
Pham, Toan
Lawrentschuk, Nathan
Inguinal lymph node dissection for penile cancer: a contemporary review
title Inguinal lymph node dissection for penile cancer: a contemporary review
title_full Inguinal lymph node dissection for penile cancer: a contemporary review
title_fullStr Inguinal lymph node dissection for penile cancer: a contemporary review
title_full_unstemmed Inguinal lymph node dissection for penile cancer: a contemporary review
title_short Inguinal lymph node dissection for penile cancer: a contemporary review
title_sort inguinal lymph node dissection for penile cancer: a contemporary review
topic Review Article on Surgery for Urologic Cancers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807325/
https://www.ncbi.nlm.nih.gov/pubmed/33457292
http://dx.doi.org/10.21037/tau.2019.08.37
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