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Synthesis and Anticancer Evaluation of Novel Derivatives of Isoxazolo[4,5-e][1,2,4]triazepine Derivatives and Potential Inhibitors of Protein Kinase C

[Image: see text] In the present study, using Thorpe’s reaction with Gewald’s modification, 4-acetylamino-5-acetyl or 5-benzoyl 3-carboxamide compounds 3 or 4 were obtained. From these compounds, two series of compounds (5, 7, and 9 and 6, 8, and 10) were obtained with 98% hydrazine. Compounds 6, 7,...

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Detalles Bibliográficos
Autores principales: Wagner, Edwin, Wietrzyk, Joanna, Psurski, Mateusz, Becan, Lilianna, Turlej, Eliza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807470/
https://www.ncbi.nlm.nih.gov/pubmed/33458465
http://dx.doi.org/10.1021/acsomega.0c03801

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