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Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles

The identification of individuals with null alleles enables studying how the loss of gene function affects infection. We previously described a non‐functional variant in SIGLEC1, which encodes the myeloid‐cell receptor Siglec‐1/CD169 implicated in HIV‐1 cell‐to‐cell transmission. Here we report a si...

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Detalles Bibliográficos
Autores principales: Benet, Susana, Gálvez, Cristina, Drobniewski, Francis, Kontsevaya, Irina, Arias, Lilibeth, Monguió‐Tortajada, Marta, Erkizia, Itziar, Urrea, Victor, Ong, Ruo‐Yan, Luquin, Marina, Dupont, Maeva, Chojnacki, Jakub, Dalmau, Judith, Cardona, Paula, Neyrolles, Olivier, Lugo‐Villarino, Geanncarlo, Vérollet, Christel, Julián, Esther, Furrer, Hansjakob, Günthard, Huldrych F., Crocker, Paul R., Tapia, Gustavo, Borràs, Francesc E., Fellay, Jacques, McLaren, Paul J., Telenti, Amalio, Cardona, Pere‐Joan, Clotet, Bonaventura, Vilaplana, Cristina, Martinez‐Picado, Javier, Izquierdo‐Useros, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807485/
https://www.ncbi.nlm.nih.gov/pubmed/33489013
http://dx.doi.org/10.1002/jev2.12046

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