Cargando…

Elevated lymphotoxin-α (TNFβ) is associated with intervertebral disc degeneration

BACKGROUND: Intervertebral disc degeneration (IVDD) is a primary cause of degenerative disc diseases; however, the mechanisms underlying the degeneration remain unclear. The immunoinflammatory response plays an important role in IVDD progression. The inflammatory cytokine lymphotoxin-α (LTα), former...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Zhu, Qiu, Chensheng, Mecca, Christina, Zhang, Yang, Bian, Jiang, Wang, Yan, Wu, Xiaolin, Wang, Tianrui, Su, Weiliang, Li, Xianglin, Zhang, Wei, Chen, Bohua, Xiang, Hongfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807514/ https://www.ncbi.nlm.nih.gov/pubmed/33441130 http://dx.doi.org/10.1186/s12891-020-03934-7

Ejemplares similares

Differential proteomic analysis of fetal and geriatric lumbar nucleus pulposus: immunoinflammation and age-related intervertebral disc degeneration
por: Qiu, Chensheng, et al.
Publicado: (2020)

Exosomes Derived from Human Urine-Derived Stem Cells Inhibit Intervertebral Disc Degeneration by Ameliorating Endoplasmic Reticulum Stress
por: Xiang, HongFei, et al.
Publicado: (2020)

Construction and assessment of bio-engineered intervertebral discs
por: Xiang, Hongfei, et al.
Publicado: (2017)

Exosomal MATN3 of Urine-Derived Stem Cells Ameliorates Intervertebral Disc Degeneration by Antisenescence Effects and Promotes NPC Proliferation and ECM Synthesis by Activating TGF-β
por: Guo, Zhu, et al.
Publicado: (2021)

Treatment of Intervertebral Disc Degeneration
por: Xin, Jingguo, et al.
Publicado: (2022)

Fexofenadine Protects Against Intervertebral Disc Degeneration Through TNF Signaling
por: Liu, Kaiwen, et al.
Publicado: (2021)

Glycine-Serine-Threonine Metabolic Axis Delays Intervertebral Disc Degeneration through Antioxidant Effects: An Imaging and Metabonomics Study
por: Wu, Xiaolin, et al.
Publicado: (2021)

Degeneration of the intervertebral disc
por: Urban, Jill PG, et al.
Publicado: (2003)

Pathomechanism of intervertebral disc degeneration
por: Oichi, Takeshi, et al.
Publicado: (2020)

Macrophages and Intervertebral Disc Degeneration
por: Koroth, Jinsha, et al.
Publicado: (2023)

Genetic factors in intervertebral disc degeneration
por: Feng, Yi, et al.
Publicado: (2016)

The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment
por: Sun, Zhen, et al.
Publicado: (2020)

The Proteolysis of ECM in Intervertebral Disc Degeneration
por: Liang, Huaizhen, et al.
Publicado: (2022)

The role of ferroptosis in intervertebral disc degeneration
por: Fan, Chunyang, et al.
Publicado: (2023)

Effect of Survivin gene therapy via lentivirus vector on the course of intervertebral disc degeneration in an in vivo rabbit model
por: Yue, Bin, et al.
Publicado: (2016)

Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
por: Le Maitre, Christine Lyn, et al.
Publicado: (2007)

Intervertebral Disc Biology: Genetic Basis of Disc Degeneration
por: Munir, Sabrina, et al.
Publicado: (2018)

Angiogenesis in the degeneration of the lumbar intervertebral disc
por: David, Gh, et al.
Publicado: (2010)

Intervertebral disc degeneration therapies in human
por: Richardson, Stephen M
Publicado: (2015)

The Role of Adipokines in Intervertebral Disc Degeneration
por: Sharma, Anirudh
Publicado: (2018)

Molecular Mechanisms of Intervertebral Disc Degeneration
por: Rider, Sean M., et al.
Publicado: (2018)

Genetic Therapy for Intervertebral Disc Degeneration
por: Roh, Eun Ji, et al.
Publicado: (2021)

Cervical intervertebral disc degeneration and dizziness
por: Liu, Tang-Hua, et al.
Publicado: (2021)

Role of Necroptosis in Intervertebral Disc Degeneration
por: Khaleque, Md Abdul, et al.
Publicado: (2023)

The Potential Role of Cytokines in Diabetic Intervertebral Disc Degeneration
por: Li, Sunlong, et al.
Publicado: (2022)

The Role of Oxidative Stress in Intervertebral Disc Degeneration
por: Cao, Guoshuai, et al.
Publicado: (2022)

Role of microRNAs in intervertebral disc degeneration (Review)
por: Yang, Fengguang, et al.
Publicado: (2021)

Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways
por: Feng, Chencheng, et al.
Publicado: (2016)

Decellularized allogeneic intervertebral disc: natural biomaterials for regenerating disc degeneration
por: Lin, Xianfeng, et al.
Publicado: (2016)

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
por: Millward-Sadler, S Jane, et al.
Publicado: (2009)

The role of ageing and oxidative stress in intervertebral disc degeneration
por: Wen, Pengfei, et al.
Publicado: (2022)

Application of stem cells combined with biomaterial in the treatment of intervertebral disc degeneration
por: Liu, Zongtai, et al.
Publicado: (2022)

Ferroptosis: A potential target for the intervention of intervertebral disc degeneration
por: Zhou, Lu-Ping, et al.
Publicado: (2022)

The Mechanisms and Functions of GDF‐5 in Intervertebral Disc Degeneration
por: Guo, Sheng, et al.
Publicado: (2021)

The Mechanism and Function of miRNA in Intervertebral Disc Degeneration
por: Wang, Chenglong, et al.
Publicado: (2022)

The circadian rhythm in intervertebral disc degeneration: an autophagy connection
por: Zhang, Tai-Wei, et al.
Publicado: (2020)

The involvement of immune system in intervertebral disc herniation and degeneration
por: Ye, Fubiao, et al.
Publicado: (2022)

lncRNAs: novel players in intervertebral disc degeneration and osteoarthritis
por: Chen, Wen‐Kang, et al.
Publicado: (2016)

Application of stem cells in the repair of intervertebral disc degeneration
por: Zhang, Wentao, et al.
Publicado: (2022)

Bovine explant model of degeneration of the intervertebral disc
por: Roberts, Sally, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_dm8q3g0nl25g506tsv80ohk5s4