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Investigation of planar image quality for a novel 2.5 MV diamond target beam from a radiotherapy linear accelerator
BACKGROUND AND PURPOSE: A commercial 2.5 MV beam has been clinically available for beam’s-eye-view imaging in radiotherapy, offering improved contrast-to-noise ratio (CNR) compared to therapeutic beams, due to the softer spectrum. Previous research suggested that imaging performance could be improve...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807593/ https://www.ncbi.nlm.nih.gov/pubmed/33458352 http://dx.doi.org/10.1016/j.phro.2020.10.007 |
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author | Borsavage, Jennifer M. Cherpak, Amanda Robar, James L. |
author_facet | Borsavage, Jennifer M. Cherpak, Amanda Robar, James L. |
author_sort | Borsavage, Jennifer M. |
collection | PubMed |
description | BACKGROUND AND PURPOSE: A commercial 2.5 MV beam has been clinically available for beam’s-eye-view imaging in radiotherapy, offering improved contrast-to-noise ratio (CNR) compared to therapeutic beams, due to the softer spectrum. Previous research suggested that imaging performance could be improved using a low-Z diamond target to reduce the self-absorption of diagnostic energy photons. The aim of this study was to 1) investigate the feasibility of two 2.5 MV diamond target beamline configurations and 2) characterize the dosimetry and planar image quality of these novel low-Z beams. MATERIALS AND METHODS: The commercial 2.5 MV beam was modified by replacing the copper target with sintered diamond. Two beamlines were investigated: a carousel-mounted diamond target beamline and a ‘conventional’ beamline, with the diamond target in the target arm. Planar image quality was assessed in terms of spatial resolution and CNR. RESULTS: Due to image artifacts, image quality could not be assessed for the carousel-mounted low-Z target beam. The ‘conventional’ 2.5 MV low-Z beam quality was softer by 2.7% compared to the commercial imaging beam, resulting in improved CNR by factors of up to 1.3 and 1.7 in thin and thick phantoms, respectively. In regard to spatial resolution, the ‘conventional’ 2.5 MV low-Z beam slightly outperformed the commercial imaging beam. CONCLUSION: With a simple modification to the 2.5 MV commercial beamline, we produced an improved energy spectrum for imaging. This 2.5 MV diamond target beam proved to be an advantageous alternative to the commercial target configuration, offering both superior resolution and CNR. |
format | Online Article Text |
id | pubmed-7807593 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-78075932021-01-14 Investigation of planar image quality for a novel 2.5 MV diamond target beam from a radiotherapy linear accelerator Borsavage, Jennifer M. Cherpak, Amanda Robar, James L. Phys Imaging Radiat Oncol Original Research Article BACKGROUND AND PURPOSE: A commercial 2.5 MV beam has been clinically available for beam’s-eye-view imaging in radiotherapy, offering improved contrast-to-noise ratio (CNR) compared to therapeutic beams, due to the softer spectrum. Previous research suggested that imaging performance could be improved using a low-Z diamond target to reduce the self-absorption of diagnostic energy photons. The aim of this study was to 1) investigate the feasibility of two 2.5 MV diamond target beamline configurations and 2) characterize the dosimetry and planar image quality of these novel low-Z beams. MATERIALS AND METHODS: The commercial 2.5 MV beam was modified by replacing the copper target with sintered diamond. Two beamlines were investigated: a carousel-mounted diamond target beamline and a ‘conventional’ beamline, with the diamond target in the target arm. Planar image quality was assessed in terms of spatial resolution and CNR. RESULTS: Due to image artifacts, image quality could not be assessed for the carousel-mounted low-Z target beam. The ‘conventional’ 2.5 MV low-Z beam quality was softer by 2.7% compared to the commercial imaging beam, resulting in improved CNR by factors of up to 1.3 and 1.7 in thin and thick phantoms, respectively. In regard to spatial resolution, the ‘conventional’ 2.5 MV low-Z beam slightly outperformed the commercial imaging beam. CONCLUSION: With a simple modification to the 2.5 MV commercial beamline, we produced an improved energy spectrum for imaging. This 2.5 MV diamond target beam proved to be an advantageous alternative to the commercial target configuration, offering both superior resolution and CNR. Elsevier 2020-11-05 /pmc/articles/PMC7807593/ /pubmed/33458352 http://dx.doi.org/10.1016/j.phro.2020.10.007 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Research Article Borsavage, Jennifer M. Cherpak, Amanda Robar, James L. Investigation of planar image quality for a novel 2.5 MV diamond target beam from a radiotherapy linear accelerator |
title | Investigation of planar image quality for a novel 2.5 MV diamond target beam from a radiotherapy linear accelerator |
title_full | Investigation of planar image quality for a novel 2.5 MV diamond target beam from a radiotherapy linear accelerator |
title_fullStr | Investigation of planar image quality for a novel 2.5 MV diamond target beam from a radiotherapy linear accelerator |
title_full_unstemmed | Investigation of planar image quality for a novel 2.5 MV diamond target beam from a radiotherapy linear accelerator |
title_short | Investigation of planar image quality for a novel 2.5 MV diamond target beam from a radiotherapy linear accelerator |
title_sort | investigation of planar image quality for a novel 2.5 mv diamond target beam from a radiotherapy linear accelerator |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807593/ https://www.ncbi.nlm.nih.gov/pubmed/33458352 http://dx.doi.org/10.1016/j.phro.2020.10.007 |
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