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Target definition in radiotherapy of prostate cancer using magnetic resonance imaging only workflow

In magnetic resonance (MR) only radiotherapy, the target delineation needs to be performed without computed tomography (CT). We investigated in thirteen patients with prostate cancer, how the clinical target volume (CTV) was affected, when the target delineation procedure was changed from using both...

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Detalles Bibliográficos
Autores principales: Gunnlaugsson, Adalsteinn, Persson, Emilia, Gustafsson, Christian, Kjellén, Elisabeth, Ambolt, Petra, Engelholm, Silke, Nilsson, Per, Olsson, Lars E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807603/
https://www.ncbi.nlm.nih.gov/pubmed/33458431
http://dx.doi.org/10.1016/j.phro.2019.03.004
Descripción
Sumario:In magnetic resonance (MR) only radiotherapy, the target delineation needs to be performed without computed tomography (CT). We investigated in thirteen patients with prostate cancer, how the clinical target volume (CTV) was affected, when the target delineation procedure was changed from using both CT and MR images to using MR images only. The mean volume of the CTV(CT/MR) was 61.0 cm(3) as compared to 49.9 cm(3) from MR-only based target delineation, corresponding to an average decrease of 18%. Our results show that CTV(MR-only) was consistently smaller than CTV(CT/MR), which has to be taken into consideration before clinical commissioning of MR-only radiotherapy.