Cargando…
Characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator
BACKGROUND AND PURPOSE: Measurement of dose delivery is essential to guarantee the safety of patients undergoing medical radiation imaging or treatment procedures. This study aimed to evaluate the ability of organic semiconductors, coupled with a plastic scintillator, to measure photon dose in clini...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807605/ https://www.ncbi.nlm.nih.gov/pubmed/33458314 http://dx.doi.org/10.1016/j.phro.2020.05.007 |
_version_ | 1783636777475506176 |
---|---|
author | Posar, Jessie A. Davis, Jeremy Brace, Owen Sellin, Paul Griffith, Matthew J. Dhez, Olivier Wilkinson, Dean Lerch, Michael L.F. Rosenfeld, Anatoly Petasecca, Marco |
author_facet | Posar, Jessie A. Davis, Jeremy Brace, Owen Sellin, Paul Griffith, Matthew J. Dhez, Olivier Wilkinson, Dean Lerch, Michael L.F. Rosenfeld, Anatoly Petasecca, Marco |
author_sort | Posar, Jessie A. |
collection | PubMed |
description | BACKGROUND AND PURPOSE: Measurement of dose delivery is essential to guarantee the safety of patients undergoing medical radiation imaging or treatment procedures. This study aimed to evaluate the ability of organic semiconductors, coupled with a plastic scintillator, to measure photon dose in clinically relevant conditions, and establish its radiation hardness. Thereby, proving organic devices are capable of being a water-equivalent, mechanically flexible, real-time dosimeter. MATERIALS AND METHODS: The shelf-life of an organic photodiode was analyzed to 40 kGy by comparison of the charge-collection-efficiency of a 520 nm light emitting diode. A non-irradiated and pre-irradiated photodiode was coupled to a plastic scintillator and their response to 6 MV photons was investigated. The dose linearity, dose-per-pulse dependence and energy dependence was characterized. Finally, the percentage depth dose (PDD) between 0.5 and 20 cm was compared with ionization chamber measurements. RESULTS: Sensitivity to 6 MV photons was (190 ± 0.28) pC/cGy and (170 ± 0.11) pC/cGy for the non-irradiated and pre-irradiated photodiode biased at −2 V. The response was independent of the dose-per-pulse between 0.031 and 0.34 mGy/pulse. An energy dependence was found for low keV energies, explained by the energy dependence of the scintillator which plateaued between 70 keV and 1.2 MeV. The PDD was within ±3% of the ionization chamber. CONCLUSION: Coupling an organic photodiode with a plastic scintillator provided reliable measurement of a range of photon energies. Dose-per-pulse and energy independence advocate their use as a dosimeter, specifically image-guided treatment without beam-quality correction factors. Degradation effects of organic semiconducting materials deteriorate sensor response but can be stabilized. |
format | Online Article Text |
id | pubmed-7807605 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-78076052021-01-14 Characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator Posar, Jessie A. Davis, Jeremy Brace, Owen Sellin, Paul Griffith, Matthew J. Dhez, Olivier Wilkinson, Dean Lerch, Michael L.F. Rosenfeld, Anatoly Petasecca, Marco Phys Imaging Radiat Oncol Original Research Article BACKGROUND AND PURPOSE: Measurement of dose delivery is essential to guarantee the safety of patients undergoing medical radiation imaging or treatment procedures. This study aimed to evaluate the ability of organic semiconductors, coupled with a plastic scintillator, to measure photon dose in clinically relevant conditions, and establish its radiation hardness. Thereby, proving organic devices are capable of being a water-equivalent, mechanically flexible, real-time dosimeter. MATERIALS AND METHODS: The shelf-life of an organic photodiode was analyzed to 40 kGy by comparison of the charge-collection-efficiency of a 520 nm light emitting diode. A non-irradiated and pre-irradiated photodiode was coupled to a plastic scintillator and their response to 6 MV photons was investigated. The dose linearity, dose-per-pulse dependence and energy dependence was characterized. Finally, the percentage depth dose (PDD) between 0.5 and 20 cm was compared with ionization chamber measurements. RESULTS: Sensitivity to 6 MV photons was (190 ± 0.28) pC/cGy and (170 ± 0.11) pC/cGy for the non-irradiated and pre-irradiated photodiode biased at −2 V. The response was independent of the dose-per-pulse between 0.031 and 0.34 mGy/pulse. An energy dependence was found for low keV energies, explained by the energy dependence of the scintillator which plateaued between 70 keV and 1.2 MeV. The PDD was within ±3% of the ionization chamber. CONCLUSION: Coupling an organic photodiode with a plastic scintillator provided reliable measurement of a range of photon energies. Dose-per-pulse and energy independence advocate their use as a dosimeter, specifically image-guided treatment without beam-quality correction factors. Degradation effects of organic semiconducting materials deteriorate sensor response but can be stabilized. Elsevier 2020-06-05 /pmc/articles/PMC7807605/ /pubmed/33458314 http://dx.doi.org/10.1016/j.phro.2020.05.007 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Research Article Posar, Jessie A. Davis, Jeremy Brace, Owen Sellin, Paul Griffith, Matthew J. Dhez, Olivier Wilkinson, Dean Lerch, Michael L.F. Rosenfeld, Anatoly Petasecca, Marco Characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator |
title | Characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator |
title_full | Characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator |
title_fullStr | Characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator |
title_full_unstemmed | Characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator |
title_short | Characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator |
title_sort | characterization of a plastic dosimeter based on organic semiconductor photodiodes and scintillator |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807605/ https://www.ncbi.nlm.nih.gov/pubmed/33458314 http://dx.doi.org/10.1016/j.phro.2020.05.007 |
work_keys_str_mv | AT posarjessiea characterizationofaplasticdosimeterbasedonorganicsemiconductorphotodiodesandscintillator AT davisjeremy characterizationofaplasticdosimeterbasedonorganicsemiconductorphotodiodesandscintillator AT braceowen characterizationofaplasticdosimeterbasedonorganicsemiconductorphotodiodesandscintillator AT sellinpaul characterizationofaplasticdosimeterbasedonorganicsemiconductorphotodiodesandscintillator AT griffithmatthewj characterizationofaplasticdosimeterbasedonorganicsemiconductorphotodiodesandscintillator AT dhezolivier characterizationofaplasticdosimeterbasedonorganicsemiconductorphotodiodesandscintillator AT wilkinsondean characterizationofaplasticdosimeterbasedonorganicsemiconductorphotodiodesandscintillator AT lerchmichaellf characterizationofaplasticdosimeterbasedonorganicsemiconductorphotodiodesandscintillator AT rosenfeldanatoly characterizationofaplasticdosimeterbasedonorganicsemiconductorphotodiodesandscintillator AT petaseccamarco characterizationofaplasticdosimeterbasedonorganicsemiconductorphotodiodesandscintillator |