Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field()

The magnetic field in magnetic resonance imaging guided radiotherapy (MRgRT) delivery systems influences charged-particle trajectories and hence the three-dimensional (3D) radiation dose distributions. This study investigated the dose-response as well as dose-rate and fractionation dependencies of s...

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Detalles Bibliográficos
Autores principales: Jensen, Morten B., Balling, Peter, Doran, Simon J., Petersen, Jørgen B.B., Wahlstedt, Isak H., Muren, Ludvig P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807676/
https://www.ncbi.nlm.nih.gov/pubmed/33458348
http://dx.doi.org/10.1016/j.phro.2020.10.003
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author Jensen, Morten B.
Balling, Peter
Doran, Simon J.
Petersen, Jørgen B.B.
Wahlstedt, Isak H.
Muren, Ludvig P.
author_facet Jensen, Morten B.
Balling, Peter
Doran, Simon J.
Petersen, Jørgen B.B.
Wahlstedt, Isak H.
Muren, Ludvig P.
author_sort Jensen, Morten B.
collection PubMed
description The magnetic field in magnetic resonance imaging guided radiotherapy (MRgRT) delivery systems influences charged-particle trajectories and hence the three-dimensional (3D) radiation dose distributions. This study investigated the dose-response as well as dose-rate and fractionation dependencies of silicone-based 3D radiochromic dosimeters for photon irradiation in a magnetic field using a 0.35 T MRgRT system. We found a linear dose response up to 22.6 Gy and no significant dose-rate dependency as a function of depth. A difference in optical response was observed for dosimeters irradiated in a single compared to multiple fractions. The dosimeter showed clinical potential for verification of MRgRT delivery.
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spelling pubmed-78076762021-01-14 Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field() Jensen, Morten B. Balling, Peter Doran, Simon J. Petersen, Jørgen B.B. Wahlstedt, Isak H. Muren, Ludvig P. Phys Imaging Radiat Oncol Short Communication The magnetic field in magnetic resonance imaging guided radiotherapy (MRgRT) delivery systems influences charged-particle trajectories and hence the three-dimensional (3D) radiation dose distributions. This study investigated the dose-response as well as dose-rate and fractionation dependencies of silicone-based 3D radiochromic dosimeters for photon irradiation in a magnetic field using a 0.35 T MRgRT system. We found a linear dose response up to 22.6 Gy and no significant dose-rate dependency as a function of depth. A difference in optical response was observed for dosimeters irradiated in a single compared to multiple fractions. The dosimeter showed clinical potential for verification of MRgRT delivery. Elsevier 2020-10-19 /pmc/articles/PMC7807676/ /pubmed/33458348 http://dx.doi.org/10.1016/j.phro.2020.10.003 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Short Communication
Jensen, Morten B.
Balling, Peter
Doran, Simon J.
Petersen, Jørgen B.B.
Wahlstedt, Isak H.
Muren, Ludvig P.
Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field()
title Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field()
title_full Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field()
title_fullStr Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field()
title_full_unstemmed Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field()
title_short Dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field()
title_sort dose response of three-dimensional silicone-based radiochromic dosimeters for photon irradiation in the presence of a magnetic field()
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807676/
https://www.ncbi.nlm.nih.gov/pubmed/33458348
http://dx.doi.org/10.1016/j.phro.2020.10.003
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