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Acute development of syringomyelia following TBM in a pediatric case
BACKGROUND: Syringomyelia secondary to tuberculous meningitis (TBM) is rarely reported, and is usually a late complication. Acute development of syringomyelia following TBM is an exceedingly rare condition with only a few cases published in adults and no previous reports in children. CASE PRESENTATI...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807712/ https://www.ncbi.nlm.nih.gov/pubmed/33446125 http://dx.doi.org/10.1186/s12887-021-02493-7 |
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author | Wen, Ningyuan Zhao, Fumin Zhu, Yu Jia, Fenglin Wan, Chaomin Wen, Yang |
author_facet | Wen, Ningyuan Zhao, Fumin Zhu, Yu Jia, Fenglin Wan, Chaomin Wen, Yang |
author_sort | Wen, Ningyuan |
collection | PubMed |
description | BACKGROUND: Syringomyelia secondary to tuberculous meningitis (TBM) is rarely reported, and is usually a late complication. Acute development of syringomyelia following TBM is an exceedingly rare condition with only a few cases published in adults and no previous reports in children. CASE PRESENTATION: We present a case of syringomyelia as an acute complication of TBM in a 12-year-old boy despite appropriate chemotherapy. The patient developed spastic paraplegia of the lower limbs with fecal and urinary retention seventeen days after the initial symptoms of TBM. He was managed successfully with continued chemotherapy and high-dose intravenous immunoglobulin (IVIG). CONCLUSIONS: This case reminds us that syrinx formation may be responsible for early neurological deterioration in children being managed for TBM. IVIG may be considered as an effective treatment option for this situation. |
format | Online Article Text |
id | pubmed-7807712 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-78077122021-01-14 Acute development of syringomyelia following TBM in a pediatric case Wen, Ningyuan Zhao, Fumin Zhu, Yu Jia, Fenglin Wan, Chaomin Wen, Yang BMC Pediatr Case Report BACKGROUND: Syringomyelia secondary to tuberculous meningitis (TBM) is rarely reported, and is usually a late complication. Acute development of syringomyelia following TBM is an exceedingly rare condition with only a few cases published in adults and no previous reports in children. CASE PRESENTATION: We present a case of syringomyelia as an acute complication of TBM in a 12-year-old boy despite appropriate chemotherapy. The patient developed spastic paraplegia of the lower limbs with fecal and urinary retention seventeen days after the initial symptoms of TBM. He was managed successfully with continued chemotherapy and high-dose intravenous immunoglobulin (IVIG). CONCLUSIONS: This case reminds us that syrinx formation may be responsible for early neurological deterioration in children being managed for TBM. IVIG may be considered as an effective treatment option for this situation. BioMed Central 2021-01-14 /pmc/articles/PMC7807712/ /pubmed/33446125 http://dx.doi.org/10.1186/s12887-021-02493-7 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Wen, Ningyuan Zhao, Fumin Zhu, Yu Jia, Fenglin Wan, Chaomin Wen, Yang Acute development of syringomyelia following TBM in a pediatric case |
title | Acute development of syringomyelia following TBM in a pediatric case |
title_full | Acute development of syringomyelia following TBM in a pediatric case |
title_fullStr | Acute development of syringomyelia following TBM in a pediatric case |
title_full_unstemmed | Acute development of syringomyelia following TBM in a pediatric case |
title_short | Acute development of syringomyelia following TBM in a pediatric case |
title_sort | acute development of syringomyelia following tbm in a pediatric case |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807712/ https://www.ncbi.nlm.nih.gov/pubmed/33446125 http://dx.doi.org/10.1186/s12887-021-02493-7 |
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