Development of BODIPY FL VH032 as a High-Affinity and Selective von Hippel–Lindau E3 Ligase Fluorescent Probe and Its Application in a Time-Resolved Fluorescence Resonance Energy-Transfer Assay

[Image: see text] The von Hippel–Lindau (VHL) tumor suppressor associates with transcription factors elongin-C and elongin-B to form the VHL–elongin-C–elongin-B protein complex and carry out its functions, such as degradation of hypoxia-inducible factors. VHL ligands are used not only to modulate hy...

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Detalles Bibliográficos
Autores principales: Lin, Wenwei, Li, Yongtao, Yang, Lei, Chen, Taosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807814/
https://www.ncbi.nlm.nih.gov/pubmed/33458521
http://dx.doi.org/10.1021/acsomega.0c05221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807814/
https://www.ncbi.nlm.nih.gov/pubmed/33458521
http://dx.doi.org/10.1021/acsomega.0c05221

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