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Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells

BACKGROUND: Osteosarcoma (OS) is a malignant tumor of the bone mostly observed in children and adolescents. The current treatment approach includes neoadjuvant and adjuvant chemotherapy; however, drug resistance often hinders therapy in OS patients. Also, the post-relapse survival of OS patients is...

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Detalles Bibliográficos
Autores principales:	Saini, Heena, Sharma, Harshita, Mukherjee, Sudeshna, Chowdhury, Shibasish, Chowdhury, Rajdeep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807844/ https://www.ncbi.nlm.nih.gov/pubmed/33446200 http://dx.doi.org/10.1186/s12935-020-01720-y

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